COLLABORATIVE ALCOHOL-RELATED LONGITUDINAL PROJECT

请求继续支持与酒精相关的合作 纵向项目--一个为期3年的项目，始建于1987年4月1日-- 它的总体目标是评估 饮酒和饮酒的流行病学和解释性研究 有问题。项目已收集了主要数据(以标准化形式记录 格式)，来自代表15个国家的41个纵向数据集，其中 在酒精研究中测试批判性假设的多学科联盟。 建立与酒精相关的协作性法律制度的理论基础 纵向项目是基于系统的迫切需要 确定纵向研究的结果可以在多大程度上 在不同年龄段、不同历史时期或不同文化中复制 描述和预测饮酒模式和问题。这项研究 问题围绕一个探索相互关系的模型进行组织 饮酒模式和问题、年龄、文化和 历史。该项目涉及五个广泛的研究议程：(1) 饮酒模式和问题的流行率、发生率和长期性 根据年龄和性别进行检查，以确定这些模式是否一致 在所有数据集上，与出生队列的影响无关， 历史时期和文化；(2)外生因素-生物、 心理学和社会学--在年龄层次内进行检查，以确定 启动和改变饮酒职业的因素，不同的队列，历史 和文化；(3)成人饮酒问题是根据 儿童时期最初测量的因素的社会行为模型 青春期。特别是，此分析旨在确定 “反社会青年行为”在多大程度上是一个一致的预测因子。 成人饮酒问题的数据集，包括重要的历史 和文化差异；(4)成人饮酒问题在 使用被领养人和一般情况下父母饮酒和酒精问题的基础 人口设计。使用被领养人的研究，假设的内部- 对可能的选择偏差和代际生物学联系进行了评估 队列效应；使用一般人口研究，交互作用 对父母饮酒行为等生活过程中的因素进行测试。 跨学科团队致力于解决这两个问题，在两个问题之间建立了联系 对这一主题的不同方法；(5)总体水平的影响 个人饮酒水平变化的潜在解释因素 通过多项纵向研究对行为进行评估。 请求支助主要分析阶段的理由如下：(A) 重申该项目的科学重要性，(B)表明 记录、协调和分析41个纵向数据的任务 与此同时，布景涉及到重大的开工和劳动力- 初期资金不足的密集工作 完成最初申请的实质性目标，以及(C) 论证分析的科学性和实用性 到目前为止已经完成了。

Continued support is requested for the Collaborative Alcohol-Related Longitudinal Project--a 3 year project originally funded April 1, 1987-- which has the overall objective of evaluating the replicability of epidemiological and explanatory research on alcohol consumption and problems. The project has assembled primary data (recorded in standardized format) from 41 longitudinal data sets, representing 15 countries, with a multidisciplinary collegium to test critical hypotheses in alcohol studies. The rationale for establishing the Collaborative Alcohol-Related Longitudinal Project was based on the critical need to systematically determine the extent to which results from longitudinal studies can be replicated across age cohorts, historical periods, or culture in the description and prediction of drinking patterns and problems. The research questions are organized around a model which explores interrelationships between drinking patterns and problems, chronological age, culture, and history. Five broad research agendas are addressed by the project: (1) The prevalence, incidence and chronicity of drinking patterns and problems by age and sex are examined to determine if these patterns are consistent across data sets, and independent of the effects of birth cohort, historical period and culture; (2) Exogenous factors--biological, psychological and sociological--are examined within age strata to identify factors which initiate and alter drinking careers across cohorts, history and culture; (3) Adult drinking problems are examined on the basis of a socio-behavioral model of factors originally measured in childhood and adolescence. In particular, this analysis is designed to determine the degree to which "antisocial youthful behavior" is a consistent predictor os adult drinking problems across data sets including significant historical and cultural variation; (4) Adult drinking problems are examined on the basis of parental drinking and alcohol problems using adoptee and general population designs. Using adoptee studies, the hypothesized inter- generational biological link is assessed for possible selection bias and cohort effects; using general population studies, the interaction of parental drinking practices and other factors in the life course is tested. Interdisciplinary teams work on both questions, forging a link between two disparate approaches to the subject; (5) The impact of aggregate-level factors as potential explanations for change in individual level drinking behavior is assessed across multiple longitudinal studies. The request for support for the major analysis phase is justified by (a) reiterating the project's scientific importance, (b) demonstrating that the task of recoding, coordinating, and analyzing the 41 longitudinal data sets, simultaneously, has involved significant ground breaking and labor- intensive work for which the initial period of funding has been inadequate to complete the original application's substantive goals, and (c) demonstrating the scientific and pragmatic significance of the analyses which have been performed to date.