EFFECTS OF PROGESTERONE ON CEH IN THE SLA INBRED MINIATURE PIG

SLA近交系小型猪群，由Ungate单位饲养和维护 对于免疫学分部，NCI通常生产一窝小猫和 展示了在标准尺寸中没有发现的各种生殖问题 猪。一种子宫疾病，囊性子宫内膜增生症(CEH)存在于 这群人。直到一岁以后才繁殖的母猪有很高的 CEH的发病率，并且不能生育。回归或 降低CEH的发生率将极大地改善生殖 牛群的表现。以前的研究表明，SLA是近亲繁殖的 小型猪的血清孕酮水平明显低于 标准大小的猪。长期给药的效果 将对CEH的孕酮进行研究。

The SLA inbred miniature pig herd, bred and maintained by the Ungulate Unit for the Immunology Branch, NCI typically produces a small litter and exhibits a variety of reproductive problems not found in the standard-sized pig. A uterine condition, cystic endometrial hyperplasia (CEH), exists in the herd. Sows that are not bred until after one year of age have a high incidence of CEH and are incapable of reproduction. Regression or reduction of the incidence of CEH would improve greatly the reproductive performance of the herd. Previous studies have shown the SLA inbred miniature pig has a serum progesterone level considerably lower than the standard-sized pig. The effects of long term administration of progesterone of CEH will be studied.