POST-TRANSFUSION HEPATITIS (PTH) IN OPEN HEART SURGERY PATIENTS

确定前瞻性随访中肝炎的发病率 心内直视手术患者接受预先处理过的血液 筛查供者转氨酶(ALT)水平，自1986年以来， 抗核心(抗HBc)抗体。ALT或ALT升高的血液单位 抗-HBc将被丢弃。肝炎发病率将进行比较 与先前研究中相同随访的患者的结果一致 它没有试图用这些来排除血液 代孕标记。在以前的研究中，血液单位升高 ALT或抗-HBc更常与受者相关 肝炎比单位正常值要高。肝炎病例将是 对病毒病原学和患者进行血清学评估 仔细观察慢性肝炎的发展情况。

To determine the incidence of hepatitis in prospectively followed open heart surgery patients receiving blood that has been pre- screened for donor transaminase (ALT) level and since 1986, for anti-core (anti-HBc) antibody. Blood units with elevated ALT or anti-HBc will be discarded. Hepatitis incidence will be compared with that of identically followed patients in previous studies in which no attempts was made to exclude blood with these surrogate markers. In previous studies blood units with elevated ALT or anti-HBc were more frequently associated with recipient hepatitis than units with normal values. Cases of hepatitis will be serologically assessed for virus etiology and patients will be carefully followed for the development of chronic hepatitis.