INFLUENCE OF LUNG DENSITY IN MANTLE TECHNIQUE CHEST IRRADIATION

放射治疗的目的是完全破坏增殖性的 所有克隆性肿瘤细胞的能力，同时不超过 对任何组织和器官的辐射损伤的耐受性。 其生物学效应取决于 吸收剂量 临床剂量测定几乎完全依赖于 基础理论模型。 在胸部照射中， 尺寸和形状依赖剂量分布 根据患者的大小、形状以及密度 分布，以及照射体积内。 需要 对后者的准确解释仍不明确 认可. 本项目旨在揭示新的光 这个问题 将对大量患者的剂量测定进行调查 使用计算机生成的剂量测定，以及相关的 测量.

Radiation therapy aims at complete destruction of the proliferative capability of all clonogenic tumor cells, while not exceeding the tolerance for radiation damage to any of the tissues and organs. The biological effects depend on the amount and distribution of absorbed dose. Clinical dosimetry depends almost entirely on an underlying theoretical model. In chest irradiation, the field size, and shape dependent dose distribution is further determined by the size, and shape of the patient, as well as density distribution, and inside the irradiated volume. The need for accurate accounting for the latter is still not unequivocally recognized. The present project is designed to shed new light on this problem. The dosimetry of a large number of patients will be investigated using computer generated dosimetry, as well as relevant measurements.