DNA binding ligands for Auger therapy and receptor imaging

我们的目标是开发非常具体的癌症放射治疗和诊断成像的新技术。该系统涉及到使用一种与放射性DNA结合药物相连的蛋白质。我们使用的放射性范围非常小--只有百万分之几毫米--允许我们选择性地杀死癌细胞，而对健康组织的伤害最小。对于诊断，我们使用较少量的辐射来获得疾病区域和程度的清晰图像，这有助于适当的治疗。

Our aim is to develop new technologies for very specific cancer radiotherapy and diagnostic imaging. The system involves the use of a protein linked to a radioactive DNA binding drug. The radioactivity we use has a very small range -a few millionths of a millimetre- allowing us to selectively kill cancer cells with minimal harm to healthy tissue. For diagnosis we use smaller amounts of radiation to obtain a clear image of the areas and extent of disease, which facilitates appropriate treatment.