The Role of Endogenous Vascular Protection Factors in Preeclampsia

子痫前期是妊娠最常见的严重并发症。它是由胎盘缺陷引起的，早期没有任何症状。目前，只有对母亲S进行定期产前检查，血压和尿液才能检测到。在其最广泛的形式中，子痫前期总体上影响约1/10的妊娠，1/50的妊娠受到严重影响。如果任由其发展和发展而不被发现，可能会危及母婴的生命。先兆子痫只能通过分娩来治愈，如果不得不早产，这会使一些婴儿面临风险。最近，科学家们已经发现血液中的化学物质(抗血管生成因子)似乎与先兆子痫的发病有关。然而，目前还不知道是什么调节了这些抗血管生成因子。如果我们能找到抑制这些因素的新机制，我们就可以提供预防性治疗。

Preeclampsia is the most common of the serious complications of pregnancy. It is caused by a defect in the placenta and is symptomless in the early stages. It is currently only detectable by regular antenatal checks on the mother s blood pressure and urine. In its widest forms, preeclampsia affects about 1 in 10 pregnancies overall and 1 in 50 pregnancies severely. It is potentially life-threatening to mother and baby if allowed to develop and progress undetected. Preeclampsia is curable only by delivery, which puts some babies at risk if they have to be delivered prematurely. Recently, scientists have identified chemicals in the blood (anti-angiogenic factors) that appear to be associated with the onset of preeclampsia. However, it is not known what regulate these anti-angiogenic factors. If we can identify novel mechanisms to inhibit these factors, we could provide preventative treatment.