20 Year Study of Skin Cancer in a Queensland Community

皮肤癌是澳大利亚最常见的癌症。虽然我们知道过度暴露在阳光下会导致皮肤癌，但皮肤癌的原因很复杂，尤其是基底细胞癌（BCC）——皮肤癌的主要类型——仍然不为人所知。阳光照射的相对强度以及与生命年龄相关的时间可能是关键因素。我们的目标是非常详细地研究这些原因，通过整理在昆士兰州Nambour的一项基于社区的皮肤癌研究中收集的20多年的信息，并对从参与者收集的皮肤癌组织进行一些实验室测试。这个为期3年的项目将充分发挥这一资源的潜力-20年的制作-其丰富的信息回答有关皮肤癌的发展和预防的问题。它应该最终为我们提供了一个比目前更清晰的“预防皮肤癌”的基本原理。此外，我们将利用从这一社区样本中收集的有关数据，评估治疗皮肤癌的一般费用和个人费用，以及皮肤癌预防措施可以节省多少卫生预算。

Skin cancers are by far the commonest cancers diagnosed in Australia. Even though it is known that sun exposure in excess causes skin cancers there are complexities about the causes, especially of basal cell carcinoma (BCC) -the major type of skin cancer- that are still not understood. Relative intensity of sun exposure and perhaps its timing with respect to age in life may well be critical factors. We aim to study these causes in very great detail by collating information that has been gathered over a 20 year period in a community-based skin cancer study in Nambour, Qld as well as performing some laboratory tests on skin cancer tissue collected from participants. This 3-year project will enable the full realisation of the potential of this esource-20 years in the making- with its wealth of information for answering questions about skin cancer decelopment and preventability. It should finally provide us with a clearer rationale for 'prevention of skin cancer' than is currently available. In addition we shall assess the costs of treatment of skin cancer in general and for the individual, and how much preventive practices for skin cancer might save the health budget, by using the releavnt data collected from this community sample.