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LOCAL AND SYSTEMIC REGULATION OF BONE DEVELOPMENT

LOCAL AND SYSTEMIC REGULATION OF BONE DEVELOPMENT
骨骼发育的局部和全身调节
批准号：
3963701
负责人：
A H REDDI
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3963701
关键词：
bone development bone marrow cartilage development cell differentiation chondrocytes crosslink developmental genetics estrogens extracellular matrix fibroblasts human tissue immunofluorescence technique monoclonal antibody normal ossification osteocytes physical chemical interaction proteoglycan skeletal pharmacology

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中文摘要
翻译
这个项目的目标是调查局部和系统的控制。 细胞外基质成分对骨骼发育的影响。当前项目 正在进行的研究包括：1)人和人的骨诱导蛋白的纯化 牛骨；2)成骨蛋白作用的特异性及其调节 其他生长因子；3)转化生长因子与骨 分化；4)胶原基质在骨诱导中的作用；5) 铝对基质诱导成骨过程中矿化的影响 6)脱矿牙本质基质对牙本质的影响 肌肉转化为软骨。
英文摘要
The objective of this project is to investigate local and systemic control of bone development by extracellular matrix components. Projects currently under study are: 1) purification of bone inductive proteins from human and bovine bone; 2) specificity of osteogenin action and its modulation by other growth factors; 3) transforming growth factors and bone differentiation; 4) role of collagenous substratum in bone induction; 5) influence of aluminum on mineralization during matrix-induced bone development, and 6) influence of demineralized dentin matrix on transformation of muscle into cartilage.
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会议论文
GROWTH AND DIFFERENTIATION FACTORS IN BONE AND CARTILAGE
LOCAL AND SYSTEMIC REGULATION OF BONE DEVELOPMENT
GROWTH AND DIFFERENTIATION FACTORS IN BONE AND CARTILAGE
GROWTH AND DIFFERENTIATION FACTORS IN BONE AND CARTILAGE
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