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Development Clinical Studies - investigation into the efficacy of Mirococept in renal transplantation

Development Clinical Studies - investigation into the efficacy of Mirococept in renal transplantation
开发临床研究-Mirococept在肾移植中的疗效调查
批准号:
G1001197/1
负责人:
Steven Sacks
金额:
$330.55万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2011
资助国家:
英国
项目状态:
已结题
起止时间:
2011 至 --

项目摘要

项目成果

Steven Sacks的其他基金

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中文摘要
翻译
这项研究旨在改善肾移植的即时功能,并改善其长期结果。一种新的分子已经被设计出来,它可以与肾脏的细胞膜结合,减少移植后的炎症反应。这将缩短患者的住院时间,并减少移植后透析的需要。也有很好的证据表明,改善肾脏的初始功能可以改善长期功能,从而改善患者的预后。这也将增加等待名单上可供移植的肾脏数量。
英文摘要
This study is designed to improve the immediate function of a kidney transplant and also to improve its longterm outcome. A novel molecule has been designed that binds to the cell membranes of the kidney and reduces the inflammatory response after transplantation. This should result in a shorter hospital stay for the patient and a reduced need for dialysis after transplantation. There is also good evidence that improving the initial function of a kidney can improve longterm fuction, thus improving the outcome for the patient. This would also increase the number of kidneys available for transplanation to those on the waiting list.
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会议论文
Efficacy of Mirococept (APT070) for Preventing Ischaemia-Reperfusion Injury associated with Kidney Transplantation-2 (EMPIRIKAL-2)
  • 批准号:
    MR/V038281/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $578.86万
  • 财政年份:
    2022
  • 负责人:
    Steven Sacks
  • 依托单位:
Measuring the impact of monoclonal antibody drugs in cancer and rheumatoid arthritis
  • 批准号:
    MC_PC_20057
  • 项目类别:
    Intramural
  • 资助金额:
    $13.71万
  • 财政年份:
    2021
  • 负责人:
    Steven Sacks
  • 依托单位:
Characterisation of glycan ligands recognised by collectin-11 in ischaemic kidney and development of a specific antagonistic probe
  • 批准号:
    MR/R010757/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $93.99万
  • 财政年份:
    2018
  • 负责人:
    Steven Sacks
  • 依托单位:
Collectin-11 as a trigger of the innate immune response in renal transplantation
  • 批准号:
    MR/M012263/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $71.41万
  • 财政年份:
    2015
  • 负责人:
    Steven Sacks
  • 依托单位:
国内基金
海外基金
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data