CHEMICAL RESEARCH IN THE DEVELOPMENT OF NEW ANTICANCER DRUGS
CHEMICAL RESEARCH IN THE DEVELOPMENT OF NEW ANTICANCER DRUGS
批准号:
4692071
负责人:
J S DRISCOLL
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
NAD(H) analog antiviral agents azacitidine aziridines cell differentiation chemical structure function cytidine cytosine arabinoside diazepine drug adverse effect drug design /synthesis /production drug metabolism drug screening /evaluation gas chromatography high performance liquid chromatography hydantoins neoplasm /cancer pharmacology nitrogen mustard nucleoside analog phosphonate pyrimidine analog
中文摘要
这项工作的目的是发现新的药物
英文摘要
The objective of this work is the discovery of new drugs which are
clinically useful against cancer. The following topics are of current
interest: 1) synthesis and evaluation of differentiating agents, 2) plasma
stability of spiromustine analogs, 3) ara-AC intracerebral antitumor
activity, 4) antitumor, antiviral and cytidine deaminase inhibition of
zebularine and 5) potentiation of AZQ CNS antitumor activity.
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CHEMICAL RESEARCH IN THE DEVELOPMENT OF NEW ANTICANCER DRUGS
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批准号:3963199
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
DIDEOXYNUCLEOSIDES AS POTENTIAL ANTI-AIDS DRUGS
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批准号:3939502
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
CNS TARGETED ANTIHIV AGENTS
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批准号:2463802
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
FLUORONUCLEOSIDES AS CNS TARGETED ANTIHIV AGENTS
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批准号:6161092
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
CHEMICAL RESEARCH IN THE DEVELOPMENT OF NEW ANTICANCER DRUGS
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批准号:3896308
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
FLUORONUCLEOSIDES AS CNS TARGETED ANTIHIV AGENTS
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批准号:6100992
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
CHEMICAL RESEARCH IN THE DEVELOPMENT OF NEW ANTICANCER DRUGS
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批准号:3939491
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
CHEMICAL RESEARCH IN THE DEVELOPMENT OF NEW ANTICANCER DRUGS
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批准号:3916541
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
DIDEOXYNUCLEOSIDES AS POTENTIAL ANTI-AIDS DRUGS
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批准号:3963220
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:J S DRISCOLL
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依托单位:
海外基金