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Supplementary funding to support the extension of the EDCTP-funded MMVC

Supplementary funding to support the extension of the EDCTP-funded MMVC
补充资金以支持 EDCTP 资助的 MMVC 的延期
批准号:
MC_PC_23003
负责人:
金额:
$65.87万
依托单位国家:
英国
项目类别:
Intramural
财政年份:
2023
资助国家:
英国
项目状态:
未结题
起止时间:
2023 至 --

项目摘要

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中文摘要
翻译
由Adrian Hill教授(牛津大学)主持的“支持延长edctp资助的‘多阶段疟疾疫苗联盟:针对寄生虫生命周期所有四个阶段的疟疾疫苗的实地效力测试’的补充资金”。由于Covid-19大流行的负面影响,研究推迟了。在这个项目中,将开发第一种多阶段疫苗,旨在针对恶性疟原虫生命周期的多个阶段,包括孢子体、肝脏、血液和蚊子阶段。多阶段疟疾疫苗的每个组成部分将在非洲的临床试验中进行测试,以确保疫苗安全、刺激免疫反应,并在我们的一些研究中有效预防疟疾。网站:https://www.jenner.ac.uk/mmvc”
英文摘要
"Supplementary funding to support the extension of the EDCTP-funded “Multi-Stage Malaria Vaccine Consortium: field efficacy testing of a malaria vaccine targeting all four stages of the parasite’s life-cycle (MMVC)” held by Professor Adrian Hill (University of Oxford). Study delayed due to the negative impacts of the Covid-19 pandemic. In this project will develop the first multi-stage vaccine designed to target multiple stages of the P. falciparum malaria parasite’s life-cycle, including the sporozoite, liver, blood and mosquito stages. Each component of the multi-stage malaria vaccine will be tested in clinical trials in Africa to ensure the vaccines are safe, stimulate an immune response, and in some of our studies, are effective in preventing malaria. Website: https://www.jenner.ac.uk/mmvc"
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