课题基金 / 基金详情

DATA ANALYSIS FROM THE VAGINAL INFECTIONS AND PREMATURITY STUDY

DATA ANALYSIS FROM THE VAGINAL INFECTIONS AND PREMATURITY STUDY
阴道感染和早产研究的数据分析
批准号:
5203296
负责人:
M A KLEBANOFF
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

项目摘要

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M A KLEBANOFF的其他基金

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中文摘要
翻译
阴道感染和早产(VIP)研究,联合申办者: NICHD和NIAID是一项前瞻性研究,旨在调查 生殖道定植与各种 微生物和早产的后续发展。 它还 结合红霉素预防早产的临床试验 在有解脲脲原体,沙眼衣原体, 和B组。 此外,VIP还收集了大量 关于可能与怀孕有关的各种因素的补充数据 结果。 本项目将分析这些因素。 进行的分析 迄今为止,包括阴道革兰氏染色的预测价值, B群链球菌的鉴定, B群链球菌携带、报告关系 体力活动和早产,治疗的效果, 红霉素对B群定植妇女妊娠结局的影响 链球菌,以及性交期间 不同生殖器定植者妊娠和早产 微生物的 分析的问题包括B组的影响 链球菌定植对妊娠结局的影响, 细菌性阴道病与妊娠结局及治疗效果 与红霉素对妊娠结局的影响 沙眼衣原体。
英文摘要
The Vaginal Infections and Prematurity (VIP) Study, jointly sponsored by NICHD and NIAID, is a prospective study designed to investigate the relationship between genital tract colonization with various microorganisms and the subsequent development of preterm birth. It also incorporates a clinical trial of erythromycin to prevent preterm birth among women colonized with Ureaplasma urealyticum, Chlamydia trachomatis, and group B streptococcus. In addition, the VIP collected a wealth of additional data on a variety of factors possibly linked to pregnancy outcome. This project will analyze these factors. Analyses undertaken to date include the predictive value of vaginal Gram stain in the identification of group B streptococcus, the descriptive epidemiology of group B streptococcal carriage, the relationship between reported physical activity and preterm birth, the effect of treatment with erythromycin on pregnancy outcome among women colonized with group B streptococci, and the association between sexual intercourse during pregnancy and preterm birth among colonized with different genital microorganisms. Questions under analysis include the effect of group B streptococcal colonization on pregnancy outcome, the association between bacterial vaginosis and pregnancy outcome, and the effect of treatment with erythromycin on pregnancy outcome among women colonized with Chlamydia trachomatis.
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