EFFECTS OF CHOLECYSTOKININ & ERYTHROMYCIN ON GASTRIC ACTIVITY

恶心和头晕目眩的症状背后的机制 腹部不适仍不得而知。胃电紊乱 节奏与晕车症状有关，尤其是恶心。 和模糊的上腹部不适。胆囊收缩素被认为是一种 “饱腹感荷尔蒙”和严重的饱腹感类似于恶心。此外, 包括红霉素在内的许多抗生素会引起恶心和上腹部 不舒服。因此，这项研究的目的是确定 缩胆囊素和红霉素引起胃电异常 都是在晕车时录下来的。肌电活动将 使用Ag-AgClEKG型电极记录，该电极将 放在上腹部。这些研究将进一步推动我们的 对CCK和CCK胃液激素机制的认识 红霉素引起的人类恶心。

The mechanisms which underlie the symptoms of nausea and vague upper abdominal discomfort remain unknown. Disturbances in gastric electrical rhythms are associated with motion sickness symptoms especially nausea and vague upper abdominal discomfort. Cholecystokinin is considered a 'satiety hormone' and severe satiety is similar to nausea. In addition, many antibiotics including erythromycin cause nausea and upper abdominal discomfort. Therefore, the purpose of this study is to determine whether cholecystokinin and erythromycin produce gastric electrical abnormalities which are recorded during motion sickness. Myoelectrical activity will be recorded by the use of Ag-AgCl EKG type electrodes which will be placed over the upper abdomen. These studies will further our understanding of the gastric and hormonal mechanism of CCK and erythromycin-induced nausea in humans.