Developing a quadrivalent HCV vaccine
Developing a quadrivalent HCV vaccine
批准号:
nhmrc : GNT1126379
负责人:
A/Pr Heidi Drummer
金额:
$65.37万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 --
中文摘要
目前还没有丙型肝炎病毒(HCV)疫苗。能够防止感染的免疫反应是可能的,这使得生产疫苗成为一个现实的目标。我们已经生产出一种独特的丙肝病毒疫苗,现在准备在新型人源化动物模型中测试我们的疫苗。我们的研究将使我们能够确定对丙型肝炎病毒提供保护的免疫反应。我们的数据对未来人类丙型肝炎疫苗研究具有重要意义。
英文摘要
A vaccine for hepatitis C virus (HCV) is not yet available. Immune responses that are able to protect against infection are possible, making the production of a vaccine a realistic goal. We have produced a unique HCV vaccine and are now poised to test our vaccine in novel humanised animal models. Our research will allow us to determine the immune responses responsible for providing protection against HCV. Our data will be highly significant for future HCV vaccine studies in humans.
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会议论文
Novel HIV-1 glycoprotein vaccines with enhanced presentation of broad neutralization epitopes
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批准号:nhmrc : 1125822
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项目类别:Project Grants
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资助金额:$50.76万
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财政年份:2017
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负责人:A/Pr Heidi Drummer
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依托单位:
Novel HIV-1 glycoprotein vaccines with enhanced presentation of broad neutralization epitopes
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批准号:nhmrc : GNT1125822
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项目类别:Project Grants
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资助金额:$74.37万
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财政年份:2017
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负责人:A/Pr Heidi Drummer
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依托单位:
Developing a quadrivalent HCV vaccine
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批准号:nhmrc : 1126379
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项目类别:Project Grants
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资助金额:$44.62万
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财政年份:2017
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负责人:A/Pr Heidi Drummer
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依托单位:
Profiling the specificity of the neutralizing antibody response in people who have long term protection from developing chronic HCV
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批准号:nhmrc : GNT1106581
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项目类别:Project Grants
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资助金额:$37.3万
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财政年份:2016
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负责人:A/Pr Heidi Drummer
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依托单位:
Profiling the specificity of the neutralizing antibody response in people who have long term protection from developing chronic HCV
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批准号:nhmrc : 1106581
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项目类别:Project Grants
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资助金额:$25.64万
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财政年份:2016
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负责人:A/Pr Heidi Drummer
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依托单位:
A universal prophylactic vaccine for Hepatitis C Virus
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批准号:nhmrc : 1080045
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项目类别:Project Grants
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资助金额:$42.9万
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财政年份:2015
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负责人:A/Pr Heidi Drummer
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依托单位:
Function and immunogenicity of the HIV-1 glycoproteins
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批准号:nhmrc : GNT1070890
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项目类别:Project Grants
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资助金额:$41.05万
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财政年份:2014
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负责人:A/Pr Heidi Drummer
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依托单位:
Studies on the activation and immunogenicity of the HIV-1 glycoproteins, gp120-gp41
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批准号:nhmrc : 1070890
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项目类别:Project Grants
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资助金额:$40.44万
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财政年份:2014
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负责人:A/Pr Heidi Drummer
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依托单位:
Understanding how Hepatitis C Virus and Human Immunodeficiency Virus mediate viral entry; rational design of novel vaccines.
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批准号:nhmrc : 1041897
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项目类别:Research Fellowships
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资助金额:$56.1万
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财政年份:2013
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负责人:A/Pr Heidi Drummer
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依托单位:
Viral entry and the development of vaccines.
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批准号:nhmrc : GNT1041897
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项目类别:Research Fellowships
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资助金额:$66.58万
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财政年份:2013
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负责人:A/Pr Heidi Drummer
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依托单位:
Roles of the hepatitis C virus glycoprotein E2 variable regions in virus entry, immunogenicity and immune evasion.
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批准号:nhmrc : 1020175
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项目类别:Project Grants
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资助金额:$45.53万
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财政年份:2012
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负责人:A/Pr Heidi Drummer
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依托单位:
Elucidating the activation mechanism of the HIV-1 envelope glycoproteins, gp120-gp41
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批准号:nhmrc : 1009809
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项目类别:NHMRC Project Grants
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资助金额:$42.47万
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财政年份:2011
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负责人:A/Pr Heidi Drummer
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依托单位:
Structural and functional role of HIV-1 gp41 terminal interactions in the membrane fusion mechanism
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批准号:nhmrc : 543125
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项目类别:NHMRC Project Grants
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资助金额:$35.32万
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财政年份:2009
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负责人:A/Pr Heidi Drummer
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依托单位:
Role of the hepatitis C virus glycoprotein E2 variable regions in viral entry and antibody mediated neutralization.
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批准号:nhmrc : 543113
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项目类别:NHMRC Project Grants
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资助金额:$36.17万
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财政年份:2009
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负责人:A/Pr Heidi Drummer
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依托单位:
Structure and function of the Hepatitis C Virus and Human Immunodeficiency Virus glycoproteins
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批准号:nhmrc : 433929
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项目类别:Career Development Fellowships
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资助金额:$31.5万
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财政年份:2008
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负责人:A/Pr Heidi Drummer
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依托单位:
Delineation of receptor-activated conformational signalling pathways in HIV-1 envelope glycoproteins
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批准号:nhmrc : 488204
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项目类别:NHMRC Project Grants
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资助金额:$55.64万
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财政年份:2008
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负责人:A/Pr Heidi Drummer
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依托单位:
Structure and function of the Hepatitis C Virus glycoproteins E1 and E2.
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批准号:nhmrc : 433913
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项目类别:NHMRC Project Grants
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资助金额:$35.6万
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财政年份:2007
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负责人:A/Pr Heidi Drummer
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依托单位:
Characterization of neutralizing antibody responses in HCV infected individuals.
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批准号:nhmrc : 381713
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项目类别:NHMRC Project Grants
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资助金额:$31.88万
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财政年份:2006
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负责人:A/Pr Heidi Drummer
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依托单位:
Receptor activated conformations of retroviral glycoproteins.
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批准号:nhmrc : 345413
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项目类别:NHMRC Project Grants
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资助金额:$32.61万
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财政年份:2005
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负责人:A/Pr Heidi Drummer
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依托单位:
Structure and function of Hepatitis C Virus glycoproteins
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批准号:nhmrc : 296200
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项目类别:NHMRC Project Grants
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资助金额:$32.06万
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财政年份:2004
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负责人:A/Pr Heidi Drummer
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依托单位:
海外基金