RENOVATION FOR MEDICAL SURGE II BUILDING

该申请要求1，000，000美元，以部分支付费用，以翻新加州大学欧文分校医学院的Med Surge II大楼。该改造项目的NIH资助部分将为15名研究人员的核心创建专门的实验室和项目空间，进行药物滥用神经科学的基础研究。该项目还将有助于大楼的整体改善，使其他生物医学研究人员受益。医学浪涌大楼是医学院校园的原始建筑之一，在生物医学科学，特别是神经科学和药理学实验室研究方面有着30年的杰出历史。虽然Med Surge II为校园提供了良好的服务，但建筑物的基础设施-包括HVAC，冷藏室，去离子水供应，应急电源容量和基本的实验室橱柜已经老化，在某些情况下过时，急需升级或更换。所要求的资金将有助于改善整个建筑物（例如，暖通空调和应急电源升级）和具体翻修（例如，实验室工作台、个案工作和通风橱）提供给由15名调查员组成的核心小组的实验室。此外，已批准的国家资金超过了目前提案的配套资金，将完成抗震升级和改进，以满足ADA标准。这些翻新旨在将Med Surge大楼恢复到现代实验室标准，并为UCI的神经科学保留重要的实验室空间，这是一个具有显著优势和校园投资的领域。所要求的资金将通过大学投资来杠杆化，以重建一个现代化的设施，能够恢复神经科学家的全部生产力，他们的研究一直受到基础设施不足的影响。Med Surge II设施的现代化不仅将确保现有设施的持续生产力，而且还将对大楼进行组织，以满足一个以药物滥用为重点的研究单位的特殊需要。

This application requests $1,000,000 to partially defray costs to renovate the Med Surge II building at the UC Irvine College of Medicine. The NIH-funded portion of this renovation project will create specialized laboratory and program space for a core of 15 researchers conducting fundamental research on the neuroscience of substance abuse. The project also will contribute to the overall improvement of the building, benefitting other biomedical researchers. The Medical Surge building is one of the original buildings of the College of Medicine campus and has a distinguished 30-year history of laboratory investigations in the biomedical sciences, particularly in Neuroscience and Pharmacology. Although Med Surge II has served the campus well, the building's infrastructure-including HVAC, cold rooms, deionized water supply, emergency power capacity, and basic laboratory cabinetry is aged, in some cases outmoded, and in severe need of upgrade or replacement. The requested funds will contribute to both improvement of the entire building (e.g., HVAC and upgrades of emergency electrical power) and specific renovations (e.g., laboratory benches, casework and fume hoods) to the laboratories of the core group of 15 investigators. In addition, approved State funding, in excess of matching funds for the current proposal, will accomplish seismic upgrades and improvements to meet ADA standards. Together these renovations are intended to restore the Med Surge building to modern laboratory standards and preserve vital laboratory space for the neurosciences at UCI, an area of significant strength and campus investment. The requested funds will be leveraged by university investment to recreate a modern facility, capable of returning to full productivity neuroscientists whose research has been steadily compromised by inadequate infrastructure. The modernization of the Med Surge II facility will not only ensure the ongoing productivity of the existing facility, but also organize the building to serve the particular needs of a research unit focused on substance abuse.