CURRENT DENSITY ELECTROENCEPHALOGRAPY

癫痫等神经系统疾病的诊断可能很快就会完成 通过密集传感器阵列的技术进步而改进 脑磁图(MEG)和脑电(EEG)。脑电波是 对公共卫生政策特别重要，因为它不是 比脑磁图或任何血流动力学(MRI， PET、SPECT)成像方式。密实的临床广泛应用 传感器阵列脑电对神经系统疾病的诊断可能 不仅通过对源代码本地化的推论实现，而且通过 最大限度地提高临床脑电图员的解释技能 通过提供高分辨率的波形和地形图 数据。具有足够的空间采样和基于3D样条线的内插 关于真实感头部几何，头皮势的拉普拉斯 表征了头骨电流密度的大脑电场。 拟议的第二阶段研究实施了PI的创新之处 具有足够的头皮脑电空间采样的电流密度脑电 使用EGI的128通道测地线传感器网络。有了这一进步 实施，电流密度脑电将成为有用辅助手段 常规脑电和偶极子建模在临床诊断和治疗中的应用 神经性疾病的管理。 建议的商业应用 传统脑电空间采样不足的问题日益突出。 天气越来越晴朗。密集阵列脑电，再加上增强的空间 电流密度测量提供的细节可能成为强大的新 临床脑电图师手中的工具。

Diagnosis of neurological disorders such as epilepsy may soon be improved by the technical advances in dense sensor array magnetoencephalography (MEG) and electroencephalography (EEG). EEG is particularly important to public health policy because it is less expensive (by factor of 10 to 100) than MEG or any hemodynamic (MRI, PET, SPECT) imaging modality. Widespread clinical application of dense sensor array EEG to the diagnosis of neurological disorders may be achieved not only through inferences on source localization, but through maximizing the clinical electroencephalographer's interpretive skills with surface EEG by providing high-resolution waveform and topographic data. With adequate spatial sampling and 3D spline interpolations based on realistic head geometry, the Laplacian of the scalp potential characterized the skull current density of the brain's electrical field. The proposed Phase II research implements the PI's innovations in current density EEG with an adequate spatial sampling of the scalp EEG with EGI's 128-channel Geodesic Sensor Net. With this advance implementation, current density EEG will be come a useful adjunct to conventional EEG and to dipole modeling in the clinical diagnosis and management of neurological disorders. PROPOSED COMMERCIAL APPLICATION The inadequate spatial sampling of conventional EEG is becoming increasing clear. Dense array EEG, coupled with the enhanced spatial detail provided by current density measure, may become powerful new tools in the hands of clinical electroencephalographers.