PHYSICAL AND DIGITAL PHANTOMS OF HUMAN HEAD

我们建议开发准确的电学特性模型 人头。物理头部模型将由以下几层构建 电阻率不同的导电塑料。嵌入电流 信号源将通过计算机接口驱动。震源波形 将包括对应于不同类型的实际脑电数据 生理状态，计算的波形将包括 对应于不同生理状态的实际脑电数据，计算 在时间和空间上都有已知统计变化的波形，以及 新皮质动力学数学模型产生的波形 功能。数字头部模型将模拟物理模型，它 将允许探索各种源几何形状和头部组织 导电性。数字头部模型将包括解剖学 配准程序以便于使用神经成像进行正演建模 数据，例如来自BrainMap数据库的数据。头部模特将提供 对当前和未来来源定位有效性的关键测试 方法：研究方法。这些模型将构成交互式培训计划的基础 在人脑电生理学的研究和临床环境中。 建议的商业应用：除用于研究外 实验室，模拟将支持培训课程 神经学住院课程，认知神经科学研究生课程， 以及神经科学本科课程。

We propose to develop accurate models of the electrical properties of the human head. The Physical Head Model will be constructed with layers of conductive plastics varying in electrical resistivity. Imbedded current sources will be driven through a computer interface. The source waveforms will include representations of actual EEG data corresponding to different physiological states, computed waveforms will include representations of actual EEG data corresponding to different physiological states, computed waveforms with known statistical variation in both time and space, and waveforms generated by mathematical models of neocortical dynamic function. The Digital Head Model will simulate the physical model, and it will allow exploration of a variety of source geometries and head tissue conductivities. The Digital Head Model will include anatomical registration procedures to facilitate forward modeling with neuroimaging data such as from the BrainMap database. The Head Models will provide critical tests of the validity of present and future source localization methods. These Models will form a basis for interactive training programs in human brain electrophysiology for both research and clinical settings. PROPOSED COMMERCIAL APPLICATION: In addition to use in research laboratories, the simulations will support training curricular for neurology residence programs., cognitive neuroscience graduate programs, and neuroscience undergraduate courses.