ENERGY RESOLVED DIGITAL HPGE X OR Y-RAY IMAGING DETECTOR

用于10至150 keV光子的成像探测器在医疗技术中有许多用途，包括肿瘤成像、SPECT和射线照相术。数字输出特别有用，因为它允许图像增强，分析，传输和存储。在第一阶段，我们提出了一种新的技术，可以捕获图像与100微米的空间分辨率和1 keV的能量分辨率或更好。这种能力将促进全新的医学诊断程序，特别是转基因小动物成像。我们的第一阶段工作证明了这种方法的可行性。在这第二阶段的努力，与保罗卢克在LBNL合作，我们将构建1厘米厚的交叉条HPGe探测器有10 × 10条，每2毫米× 20毫米。我们将开发冷却FET前置放大器具有低噪声和大带宽特性，特别是这种方法所需的。我们还将开发模拟滤波电子设备来调节探测器的新信号，并采用数字脉冲处理电子设备以高达10/6 cps的速率采集这些信号。最后，我们将设计程序来测试检测器的线性度，并开发处理算法来完善这一质量。第二阶段将以一个经过测试的工作原型结束。第三阶段将主要涉及生产工程方面的工作。拟定商业应用：作为具有100微米空间分辨率的能量分辨数字探测器，所提出的探测器技术可以找到许多医学应用，包括SPECT、小型哺乳动物的能量分辨血管造影、啮齿动物骨骼的骨密度测定以及小型手持式伽马相机。非医学应用包括非破坏性测试、天体物理伽马成像、核清理用途和x射线衍射探测器。

Imaging detectors for 10 to 150 keV photons have many uses in medical technology, including tumor imaging, SPECT, and radiography. Digital output is particularly useful since it allows image enhancement, analysis, transmission and storage. In Phase I we proposed a new technology that could capture images with 100 microm spatial resolution and 1 keV energy resolution or better. This capability would facilitate entirely new classes of medical diagnostic procedures, particularly for transgenic small animal imaging. Our Phase I work demonstrated the feasibility of this approach. In this Phase II effort, collaborating with Paul Luke at LBNL, we will construct 1 cm thick crossed-strip HPGe detectors having 10 x 10 strips, each 2 mm x 20 mm. We will develop cooled FET preamplifiers having low noise and large bandwidth properties specifically required by this approach. We will also develop analog filtering electronics to condition the detector's novel signals and employ digital pulse processing electronics to acquire these signals at rates up to 10/6 cps. Finally, we will devise procedures to test the detector's linearity and develop processing algorithms to perfect this quality. Phase II will conclude with a working and tested prototype. Phase III will entail primarily production engineering efforts. PROPOSED COMMERCIAL APPLICATION: As an energy resolved digital detector with 100 microm spatial resolution, the proposed detector technology could find many medical applications, including SPECT, energy resolved angiography for small mammals, bone densitometry on rodent bones, and small, hand-held gamma cameras. Non-medical applications would include non-destructive testing, astrophysical gamma imaging, nuclear cleanup uses, and x-ray diffraction detectors.