INTEGRATED TRAINING IN REPRODUCTIVE ENDOCRINOLOGY

拟议方案旨在每年为两名研究生级别的博士后研究员和四名博士后研究员提供生殖生物学方面的培训。受训人员有望在基础科学或临床科室从事学术研究工作。在过去的15年里，该培训计划已经实施了74名博士后实习生(48名医学博士，8名医学博士/博士，18名/博士)。22名研究生接受了培训。学员在向生殖内分泌学中心提出正式申请后由一个五人指导委员会挑选，对于博士前学生，则是生物医学科学研究生计划的正式申请。研究生将继续攻读生物医学博士学位。博士后培训将提供给相关学科的博士候选人，以及临床培训的拥有医学博士学位并曾接受过妇产科、儿科或内科专业培训的科学家。所有入职研究员将由指导团队指导，以确定适当的课程工作，并启动和跟踪研究进展。没有接受过研究生教育的医学博士研究生将在三年奖学金的第一年参加研究生水平的课程并进行研究。所有学员将参加每周一次的生殖生物学研讨会和研究工作坊，并将学习分子和细胞生殖生物学课程。研究培训将由生殖内分泌学中心的16名成员提供，他们在加州大学旧金山分校医学和牙科学院担任基础科学和临床系的教职。目前的研究项目涉及生殖生物学的重要问题，包括性别决定、生殖道发育、卵巢和睾丸的生物学、正常和异常生殖功能的内分泌调节以及不孕症的遗传学。生殖内分泌学中心(REC)实验室和办公室位于健康科学教学和研究大楼的两层，占地约13,000平方英尺。此外，还有灵长类设施、临床研究单位和转基因屏障设施可供研究。组织学、激素测量、蛋白质分离和测序以及分子生物学核心也可用于培训。

The proposed program is designed to furnish training for two graduate level predoctoral and four postdoctoral fellows per year in reproductive biology. Trainees are expected to go on to academic investigative careers in basic science or clinical departments. The training program has been operative for the past 15 years during which time 74 postdoctoral trainees (48 M.D., 8 M.D./Ph.D.,18/Ph.D.) and 22 graduate students have received training. Trainees are selected by a five member Steering Committee following formal application to the Reproductive Endocrinology Center and, in the case of predoctoral students, to the Biomedical Sciences Graduate Program. Graduate students will pursue a course of study leading to the Ph.D. degree in Biomedical Sciences. Postdoctoral training will be offered to Ph.D. candidates in related disciplines, and also to clinically trained scientists with M.D. degrees and prior specialty training in Obstetrics and Gynecology, Pediatrics or Internal Medicine. All entering fellows will be guided by a mentoring team to determine appropriate course work, and to initiate and follow research progress. M.D. fellows with no prior graduate education will spend the first year of a 3 year fellowship attending graduate level courses and performing research. All trainees will participate in the weekly Reproductive Biology Seminar Program and Research Workshop and will take the Molecular and Cellular Reproductive Biology Course. Research training will be provided by the 16 members of the Reproductive Endocrinology Center who hold faculty positions at UCSF School of Medicine and Dentistry in both basic science and clinical departments. Current research programs address important issues in reproductive biology including: sex determination, development of the reproductive tract, biology of the ovary and testes, endocrine regulation of normal and abnormal reproductive function and genetics of infertility. The Reproductive Endocrinology Center (REC) laboratories and offices consist of approximately 13,000 square feet on two floors of the Health Sciences Instruction and Research Building. In addition a primate facility, clinical research unit and transgenic barrier facility are available for studies. Histology, hormone measurement, protein separation and sequencing, and molecular biology cores also are available for training.