MASS SPECTROMETER OPERATIONS

在JEOL上进行了一系列单独的培训课程 HX-110和AX-505双聚焦质谱仪，以及 PerSeptive生物系统公司和维斯特克MALDI质谱仪。个体 为9名研究生提供了实践培训，4个职位 博士生研究员和一名客座教授。培训 包括质谱计的一般操作和特定的 与个人研究项目相关的技术。这些技术 包括GC-MS(EI、ECNI、SIM和HR)FAB(HR和LR)、FD和各种 MS/MS实验。我们还提供一些基本的培训 生化方法，如微孔高效液相色谱和酶 与MALDI-MS一起用于蛋白质的消化 表征(例如，多肽质量图谱)。

A series of separate training sessions were conducted on the JEOL HX-110 and AX-505 double focussing mass spectrometers, as well as the PerSeptive Biosystems and Vestec MALDI mass spectrometers. Individual hands-on training was provided for nine graduate students, four post doctoral researchers, and one visiting professor. The training included both general operation of mass spectrometers and specific techniques related to individual research projects. These techniques included GC-MS (EI, ECNI, SIM, and HR) FAB (HR and LR), FD and various MS/MS experiments. We are also providing training in some basic biochemical methodologies, such as microbore HPLC and enzymatic digestions, which are used in concert with MALDI-MS for protein characterization (e.g., peptide mass mapping).