ENZYMOLOGY OF MICROCIN B17 BIOSYNTHESIS

D.吉布森是希伯来大学的教授。他成为了 在攻读硕士学位期间对质谱学有丰富的经验， 一直使用仪器技术，特别是核磁共振，贯穿于他的 职业生涯。在他目前在The Resources的休假期间，他将更新 他早期的经验是通过实施需要MALDI和 ESI，在与他自己的研究兴趣相关的领域， 抗癌药物与寡核苷酸的相互作用 与资源和外部人员的协作。当他回来时 对于以色列，他的机构正计划购买MALDI和ESI 质谱仪，吉布森教授将负责 对这些新工具的监督。N.Kelleher获得博士学位 康奈尔大学在F.W.McLafferty和T. 贝格利。他的论文项目集中在性质的确定上。 电喷雾电离傅里叶变换离子对蛋白质的分析 回旋共振质谱仪。他目前是博士后 哈佛医学院C.T.沃尔什研究组成员。 为了拓宽他在各种质谱学方面的经验 技术，凯莱赫博士现在正在进行的实验包括 电喷雾电离三重四极串联质谱仪 基质辅助激光解吸/电离飞行时间质量 在资源部门员工的指导下，进行光谱分析。

D. Gibson is a professor at the Hebrew University. He became experienced with mass spectrometry during his MS degree program, and has used instrumental techniques, particularly NMR, throughout his career. During his current sabbatical at the Resource, he will update his earlier experience by carrying out projects that require MALDI and ESI, both in areas related to his own research interests, the interactions of anticancer agents with oligonucleotides, and in collaborations with Resource and external personnel. Upon his return to Israel, his institution is planning to purchase both MALDI and ESI mass spectrometers, and Prof. Gibson will assume responsibility for oversight of these new instruments. N. Kelleher received his PhD at Cornell University under the direction of F. W. McLafferty and T. Begley. His thesis project centered on determinations of properties of proteins using electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. He is presently a postdoctoral fellow in the research group of C. T. Walsh at Harvard Medical School. In order to broaden his experience with a variety of mass spectral techniques, Dr. Kelleher is now undertaking experiments that involve electrospray ionization triple quadrupole tandem mass spectrometry and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, under the guidance of Resource staff.