ECHO PLANAR CONTRAST ENHANCED 3D MR ANGIOGRAPHY

引言：本研究的目的是评估 快速螺旋增强动态增强磁共振成像技术的应用能力 采集以测量活体正常的人肾血流量。十五 对正常志愿者进行动态增强MRI检查。方法： 采用快速螺旋采集的屏气技术[螺旋-PC]， 以及一种电影-PC技术，它允许同时分辨心脏和 采用快速螺旋采集的呼吸周期[SPR-PC]是 受雇的。计算每个患者的总动脉肾血流量 个人的。通过标准技术测量肾脏血流量 对每个受试者获得相同的多环芳烃清除-红细胞压积 当天作为核磁共振检查。结果：两组间的一致性正常 PAH清除技术的肾血流量测定及 采用螺旋捕获的各种Cine-PC技术非常好， 与SPR-PC技术给出了最好的一致性，当数据结束时 对保质期进行分析。一致的两个标准差范围 后一种技术与PAH清除-红细胞压积之间 是115%。结论：采用快速螺旋的Cine-PC技术 采集似乎能够对人体进行准确的活体测量 肾血流量。这些技术给人们带来了很大的希望 肾血流量可能减少的临床测量 情况如肾动脉狭窄。

Introduction: The purpose of this study was assessment of the ability of techniques of Cine-phase contrast MRI using rapid spiral acquisition to measure normal human renal blood flow in vivo. Fifteen normal volunteers were studies with Cine-phase contrast MRI. Methods: A breathheld technique employing rapid spiral acquisition [Spiral-PC], and a Cine-PC technique which allowed resolution of both cardiac and respiratory cycles employing rapid spiral acquisition [SPR-PC] were employed. Total arterial renal blood flow was calculated for each individual. Measurements of renal blood flow via standard techniques of PAH clearance-hematrocrit were obtained for each subject the same day as the MRI examinations. Results: The agreement between normal renal blood flow measurements for the PAH clearance techniques and the various Cine-PC techniques employing spiral acquisition was very good, with the SPR-PC technique giving the best agreement, when data in end expiration was analyzed. A two standard deviation range of agreement between this latter technique with the PAH clearance-hematocrit value was 115%. Conclusions: The Cine-PC techniques employing rapid spiral acquisitions appear capable of accurate in vivo measurement of human renal blood flow. The techniques give a good deal of promise for clinical measurement of renal blood flow which may be reduced in such conditions as renal artery stenosis.