课题基金 / 基金详情

Development and refinement of neural connections in the adult brain in health and disease

Development and refinement of neural connections in the adult brain in health and disease
健康和疾病中成人大脑神经连接的发展和完善
批准号:
nhmrc : 569575
负责人:
Prof Pankaj Sah
金额:
$537.55万
依托单位国家:
澳大利亚
项目类别:
Programs
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2013-12-31

项目摘要

项目成果

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中文摘要
翻译
我们的团队将使用创新的方法,如先进的成像、细胞分类和动物模型的开发,来确定新的神经元是如何产生的,它们是如何到达大脑的不同部位的,以及它们是如何整合到现有的大脑回路中的。这些发现将为治疗衰老和病理过程中的脑损伤指明新的途径。由于团队成员之前曾参与过分子发现到临床试验的进展,因此我们也处于与生物制药行业合作开发这些发现的有利地位。
英文摘要
Our group will use innovative approaches such as advanced imaging and cell-sorting and development of animal models to determine how new neurons are generated, how they travel to different parts of the brain and how they integrate into the existing brain circuitry. These discoveries will point to new ways in which to treat brain damage both during ageing and during pathology. Since team members have previously been involved in progressing molecular discovery to clinical trials, we are also in a good position to exploit these discoveries in partnership with the biopharmaceutical industry.
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会议论文
Network activity and the role of NMDA receptors in associative learning
  • 批准号:
    DP220102377
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $54.96万
  • 财政年份:
    2022
  • 负责人:
    Prof Pankaj Sah
  • 依托单位:
Brain connectome: from synapse, large-scale network to behaviour
  • 批准号:
    DP180103319
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $25.23万
  • 财政年份:
    2018
  • 负责人:
    Prof Pankaj Sah
  • 依托单位:
Neural circuits that mediate fear extinction
  • 批准号:
    nhmrc : 1128427
  • 项目类别:
    Project Grants
  • 资助金额:
    $64.34万
  • 财政年份:
    2017
  • 负责人:
    Prof Pankaj Sah
  • 依托单位:
Neural circuits that mediate fear extinction
  • 批准号:
    nhmrc : GNT1128427
  • 项目类别:
    Project Grants
  • 资助金额:
    $94.17万
  • 财政年份:
    2017
  • 负责人:
    Prof Pankaj Sah
  • 依托单位:
海外基金