CANCER RESEARCH TRAINING IN MOLECULAR BIOLOGY

本申请书是为继续在 癌症分子生物学，已经运作了19年， 是NCI指定的癌症研究中心的组成部分 (P30 CA 44579）在弗吉尼亚大学健康科学中心。 培训是在博士预科水平导致博士学位进行。 学位，以及在博士后水平，对于那些谁已经持有 的博士或者医学博士℃下虽然节目的中心主题是 癌症的生物学，重点放在深入的培训， 相关分支学科，包括遗传学、分子和细胞 生物学，生物化学，膜结构和功能，病毒肿瘤学， 免疫学、信号转导、发育和分化，以及 药物作用和毒性的分子机制。博士预科 学生，培训是基于核心课程（包括一门课程， 癌症的分子基础），这是由专门的 课程，研讨会，专题讨论会，期刊俱乐部，教学经验， 参加国家和州会议，并完成 独立研究项目。博士后培养强调实验室 研究和参加研讨会、期刊俱乐部等，和 年轻学员的指导。博士学位可以从任何 参与的部门或学位授予计划，包括 微生物学、生物化学、药理学、生理学、细胞生物学和 解剖学、生物物理学和神经科学。研究导师来自 这些部门和计划的教师，重点是成员 微生物学系和其他涉及 癌症相关的研究。博士预科生度 从直接申请微生物学博士学位的学生中挑选 计划，从那些申请入学的跨学科课程 (such细胞与分子生物学、分子医学和医学 科学家培训计划），并从那些谁正在接受研究 在培训学院的实验室进行培训，无论 部门考生是根据学业成绩录取的， GRE成绩，推荐信，动机，兴趣和研究 体验.基于扩大的教师队伍，将提高国际- 纪律和癌症相关的培训计划，支持重点 18 PhD研究生和5名博士后研究生， 所请求可用于此培训的设施是国家的- 艺术和支持的核心实验室过多。的目标 该计划是准备选定的个人的职业生涯在教学和 与癌症生物学问题相关的基础研究。

This application is for continuation of a Training Program in the Molecular Biology of Cancer, which has been in operation for 19 years and is an integral component of the NCI-designated Cancer Research Center (P30 CA44579) at the University of Virginia Health Sciences Center. Training is conducted at the predoctoral level leading to the Ph.D. degree, as well as at the postdoctoral level, for those who already hold the Ph.D. or M.D. degree. Although the central theme of the program is the biology of cancer, emphasis is placed on in-depth training in relevant subdisciplines, including genetics, molecular and cellular biology, biochemistry, membrane structure and function, viral oncology, immunology, signal transduction, development and differentiation, and molecular mechanisms of drug action and toxicity. For pre-doctoral students, training is based on a Core Curriculum (including a course on the Molecular Basis of Cancer), which is augmented by specialized courses, seminars, symposia, journal clubs, teaching experiences, participation in national and state meetings, and completion of an independent research project. Postdoctoral training emphasizes laboratory research and participation in seminars, journal clubs, etc., and instruction of younger trainees. Ph.D. degrees can be obtained from any of the participating departments or degree-granting programs, including Microbiology, Biochemistry, Pharmacology, Physiology, Cell Biology and Anatomy, Biophysics, and Neuroscience. Research mentors are drawn from the faculty of these Departments and Programs, with emphasis on members of the Microbiology Department and other Departments who are involved in cancer-related research. Predoctoral candidates for the Ph.D. degree are selected from among students applying directly to the Microbiology Ph.D. program, from those applying for admission to interdisciplinary programs (such as Cell and Molecular Biology, Molecular Medicine, and Medical Scientist Training Programs), and from those who are receiving research training in the laboratories of the Training Faculty, regardless of department. Candidates are admitted on the basis of academic achievement, GRE scores, letters of recommendation, motivation, interest, and research experience. Based on an expanded faculty that will enhance the inter- disciplinary and cancer-related focus of the training program, support for 18 Ph.D. candidates and 5 postdoctoral trainees per year is requested. The facilities available for this training are state-of-the- art and are supported by a plethora of Core Laboratories. The goal of the Program is to prepare selected individuals for careers in teaching and basic research relevant to problems in cancer biology.