Robust Control and Filtering for Regulation of Flow in Implantable Rotary Blood Pumps

该项目旨在推导和实现一种新颖的、健壮的和非侵入性的动态建模、状态估计和生理控制，以使左心室辅助装置能够以自然的Frank-Starling方式工作。拟议的多目标平台将利用来自左心室辅助装置的无传感器反馈信号(测量)来设计一个健壮、自适应和反应灵敏的控制系统，以有效地控制泵的运行，以满足人体的生理需求、扰动和应对不断变化的生理需求。例如，这将使心力衰竭患者恢复正常的日常生活，并最大限度地减少对临床工作人员持续监督的需要。

This project aims to derive and implement a novel, robust and non-invasive dynamical modelling, state estimation and physiological control to enable a left ventricular assist device to behave in a natural Frank-Starling like manner. The proposed multi-objective platforms will utilise sensorless feedback signals (measurements) from the left ventricular assist device to design a robust, adaptive and responsive control system that effectively controls the operation of the pump to meet the body's physiological needs, perturbations and to cope with changing physiological demands. This will allow, for example, heart failure patients to resume their normal daily lives and minimise the need for continuous supervision by clinical staff.