ADAPTING BEHAVIORAL MARITAL THERAPY TO TREAT DRUG ABUSE

R01DA10835-01的第二次修订，最初提交时间为2/96 (分数是225)然后是2/97(分数是179)，是3年，第一阶段 研究计划是针对NIDA行为疗法的 发展计划。它开发了一种婚姻治疗模式 治疗滥用药物或依赖药物的男性及其女性 合作伙伴，通过修改目前用于治疗的类似模型 酒精依赖。评估/治疗手册将是 通过治疗三个队列，每个队列8对夫妇。变化 在基于经验的方案中，每个队列将是 纳入治疗手册，以供后续队列使用。 这项研究的总体目标是开始有计划地 一种有前途的行为伴侣药物治疗方法的研究进展 成瘾(BCTD)，并生成治疗手册，相关 第二阶段研究的材料和描述性数据。特定的 主要目标是：(1)开发一个可行的、人性化的 独立的门诊患者认知治疗方案- 药物成瘾的行为伴侣疗法；(2)发展 基线(BL)和后续(FU)评估电池 合作伙伴，研究精神病理学，药物使用， 和婚姻关系的质量，对BCTD的反应，以及 (3)生成自我报告、访谈和观察数据 每对夫妇，这样我们就可以仔细地描述样品中的 基本法条款和治疗后的特点，以及婚姻 互动特别涉及到我们的变革模式。这些 描述性数据将有助于治疗方法的开发 适用于广泛药物滥用的议定书 个人，以及与变化相关的假设，这可以是 在后来的第二阶段研究中进行了测试。具体的次要目标是： (4)制定治疗师的选拔和培训方案； (5)发展治疗师忠诚度/能力的量度；。(6) 制定治疗完整性的衡量标准，以及(7)评估 对该样本进行跟踪调查的可行性。研究设计和 方法：首先，我们将编写BCTD药物治疗手册 误用，BL和FU评估电池，培训方案 治疗师，以及一系列治疗和治疗师流程 措施。评估/治疗方案将包括 评估24次门诊联合会议、治疗后FU和 离职面试，以及为期3个月的付福和离职面试。首字母 协议的版本将在前六个月制定 几个月，通过修改现有的酒精行为方案 夫妻治疗。在第一年下半年，8 将招募夫妇，并将试行初始方案和 已修订。另外八对夫妇将组成第二个队列，他们将 执行修订后的评估/治疗方案 资助金的第二年。然后，手册将再次修订，并 最终的8对选手将试行“最接近决赛”的版本。 在过去一年的评估/治疗/跟进一揽子计划 奖助金。最终修改将根据第三次测试的结果进行 编队飞行员，手册和协议将准备用于 随后对治疗进行了测试。

This second revision of R01DA10835-01, originally submitted 2/96 (score was 225) then 2/97 (score was 179), is a 3 year, Stage I research plan is in response to the NIDA Behavioral Therapies Development Program. It develops a marital therapy model of treatment for drug abusing or dependent males and their female partners, by modifying a similar model currently used to treat alcohol dependence. The assessment/treatment manual will be developed by treating three cohorts of 8 couples each. Changes in the protocol based on experiences with each cohort will be incorporated into the treatment manual for the subsequent cohort. Broad objectives of the study are to begin programmatic development of a promising behavioral couples treatment for drug addiction (BCTD), and to generate a treatment manual, related materials, and descriptive data for Stage II research. Specific primary goals are: (1) to develop a feasible, manualized treatment protocol for stand-alone, outpatient cognitive- behavioral couples therapy for drug addiction; (2) to develop baseline (BL) and follow-up (FU) assessment batteries for both partners, to study the effects of psychopathology, substance use, and quality of the marital relationship, on response to BCTD, and (3) to generate self-report, interview, and observational data on each couple, so that we can carefully describe the sample in terms of BL and post-treatment characteristics, and marital interaction specifically related our model of change. These descriptive data will facilitate development of a treatment protocol that is applicable to wide range of drug abusing individuals, and of hypotheses related to change, that can be tested in later Stage II studies. Specific secondary goals are: (4) to develop selection and training protocols for therapists; (5) to develop a measure of therapist adherence/competence; (6) to develop a measure of treatment integrity, and (7) to evaluate the feasibility of following up this sample. Research Design and Methods: First, we will prepare a BCTD treatment manual for drug misuse, BL and FU assessment batteries, a training protocol for therapists, and a battery of treatment and therapist process measures. The assessment/treatment package will include BL assessment 24 outpatient conjoint sessions, post-treatment FU and exit interview, and a 3 month FU and exit interview. The initial version of the protocols will be developed in the first six months, by modifying existing protocols for alcohol behavioral couples therapy. During the second half of the first year, 8 couples will be recruited and the initial protocol will be piloted and revised. Eight more couples will comprise the second cohort and will be administered the revised assessment/treatment protocol during the second year of the grant. The manual will then be revised again, and the final cohort of 8 couples will pilot the "closest to final" version of the assessment/treatment/ follow-up package during the last year of the grant. Final revisions will be made based on results from the third cohort pilot, and the manual and protocols will be prepared for used in subsequent tests of the treatment.