FASEB CONFERENCE/MOLECULAR BIOPHYSICS OF MEMBRANES

描述：（申请人摘要中的逐字记录）拟议的FASEB夏季 题为"细胞膜的分子生物物理学"的会议将于 2000年7月15日至20日在佛蒙特州萨克斯顿河的佛蒙特学院。与 基因组数据库中序列信息的积累，它已成为 很明显，大量的基因致力于指定 膜蛋白此外，膜蛋白及其脂质环境具有 在结构生物学、生物化学和 生物物理学，考虑到溶解度，稳定性和纯化的困难， 这些分子物种的出现，强调需要新的方法， 和想法。在这次会议上，应用来自 生物物理化学的问题，在膜生物学的解决。几 会议以比以往任何时候都更深入和严谨的方式讨论这个问题。 这是过去的会议，计划在下一次迭代。 通过提供一个场所，深入处理这一主题的基本思想 区域，为年轻科学家的教育创造了环境， 该领域，以及为思想的发展更高级的数字。 重点将放在使用定量方法， 了解结构和机制。据认为，发展 详细的分析是发展的最重要的途径， 在生物学这一重要领域中推广了一些想法。

DESCRIPTION: (Verbatim from the Applicant's Abstract) The proposed FASEB summer meeting entitled "Molecular Biophysics of Cellular Membranes" will be held on July 15-20, 2000 at the Vermont Academy in Saxton's River, Vermont. With the accumulation of sequence information in genomic databases, it has become apparent that a very large number of genes are devoted to the specification of membrane proteins. Further, membrane proteins and their lipid environment have yielded more slowly to the efforts of structural biology, biochemistry, and biophysics, given the difficulties of solubility, stability, and purification that arise for these molecular species, emphasizing the need for new approaches and ideas. In this conference, the important subject of applying ideas from biophysical chemistry to problems in membrane biology is addressed. Few meetings approach the subject with the depth and rigor than has characterized this meeting in the past and that is planned for the next iteration. By providing a venue for a deep treatment of fundamental ideas in this subject area, an environment is created for the education of young scientists entering the field, as well as for the development of thinking by more senior figures. An emphasis will be placed on the use of quantitative approaches to an understanding of structure and mechanism. It is felt that the development of detailed analysis is the most important pathway to the development of generalizing ideas in this important field of biology.