PATHOBIOLOGY OF DIGESTIVE DISEASES

提出了一个独特的培养博士后和博士后的计划 消化系统疾病病原学研究人员 疾病，并为医生提供深入的跨学科 与消化系统疾病相关的现代生物学培训 病理生物学。医生花三年时间进行个性化治疗 与以下方面有关的研究培训、课程和实验室轮换 在咨询委员会的监督下的特定利益。 培训由21名经验丰富的讲师指导，这些讲师与 塔夫茨大学生理学-病理生理学系 医学院。教职员工都是基础科学家，基本上- 以内科医生为导向的科学家，他们对提议的 新的计划，并拥有大量的研究记录和支持 在与消化系统疾病相关的领域。主要的研究目标是 为了了解细胞表面的事件(即，泵， 通道、接收器等)控制基因表达的相关因素 信号转导、再生、分化与极性 在生理条件和疾病状态下。该计划 包括研讨会、期刊俱乐部和研究生课程，包括 为博士生和研究员提供独特的病理生物学课程。我们的 目标是弥合生物学上的重大进步和 它们在人类消化系统疾病中的应用。我们寻求培养博士 将独立从事临床工作的毕业生和医生 调查人员，而不是为他们。主要目标是减少 将基础科学家与他们的 临床同事，从而加强知识的转移 从一个学科到另一个学科。

A unique program is proposed to train pre- and postdoctoral PhD fellows for research careers in the pathobiology of digestive diseases, and to provide physicians with in-depth interdisciplinary training in modern biology as related to digestive disease pathobiology. Physicians spend three years in individualized research training, courses and laboratory rotations related to specific interests under supervision of an advisory committee. Training is supervised by 21 experienced preceptors associated with the Department of Physiology-Pathophysiology at Tufts University School of Medicine. Faculty are basic scientists and basically- oriented physician scientists who share enthusiasm for the proposed novel program and who have substantial research records and support in areas related to digestive diseases. The major research goal is to understand how events on the surface of cells (i.e., pumps, channels, receptors, etc.) control gene expression as related to signal transduction, regeneration, differentiation and polarity under physiologic conditions and in disease states. The program includes seminars, journal club and graduate courses including a unique program in Pathobiology for PhD Students and Fellows. Our goal is to bridge the gap between major advances in biology and their application to human digestive diseases. We seek to train PhD graduates and physicians who will work independently with clinical investigators rather than for them. The major goal is to reduce the intellectual barriers which separate basic scientists from their clinical colleagues and thereby enhance the transfer of knowledge from one discipline to another.