RESILIENCE & QUALITY OF LIFE IN ADOLESCENTS WITH CANCER

描述：(改编自调查员摘要) 儿童癌症的存活率比过去有了很大提高 在美国生活了20年。根据癌症的类型，58%-88% 的儿童和青少年将是长期的、无病的幸存者。 虽然这些统计数据令人鼓舞，但许多癌症的性质和病程 已经从不可避免的致命疾病变成了慢性疾病 继续携带着威胁生命的潜力。《美国癌症》 社会已经确定了青少年癌症护理，包括心理社会护理， 作为研究的优先事项。然而，令人惊讶的是，很少有基于数据的研究 报告了青少年癌症患者的心理社会适应情况。在……里面 此外，对AWC进行系统计划的心理社会干预研究 是罕见的，尽管在过去的20年里，这种干预措施在 患有癌症的成年人，显示出有希望的结果。有20多万个童年 癌症幸存者，预计到2000年将达到每250人中就有1人， 当务之急是让患有癌症的青少年的适应问题 地址。本研究的目的是：1)纵向考察， 弹性和生活质量的变化的性质和模式 青少年心理复原力模型(ARM)在青少年中的应用分析 癌症；以及，2)评估恢复力和 家庭和青少年网络(FAN)带来的生活质量变化 旨在通过以下方式提高复原力和生活质量的干预措施 个人、家庭和社会的保护因素在手臂上。这项研究 设计包含两个组成部分。回答有关关系和关系的问题 个人、家庭和社会保护因素之间的因果关系， 与疾病相关的个人风险因素，以及复原力和质量 11-19岁青少年癌症患者的生活状况 将采用纵向描述性设计。青少年将会是 从确诊到第一个患癌症的人。在 项目的最后两年半，在完成了改进和试点工作之后 风机干预，将采用纵向实验设计 实现以评估ARM中的因素中发生的更改 家庭和青少年网络(FAN)干预的结果是 有针对性地加强个人、家庭和社会保护因素 对与疾病相关的风险因素和个人风险因素进行建模并将其降至最低。这个 建议总样本量为243人。将对学习目标进行分析 通过：1)生长曲线分析评估初始状态， 变化率和稳定性；2)增长曲线的公因子建模 参数；以及3)随时间变化因素的结构建模，并作为 干预的结果。

DESCRIPTION: (Adapted from investigator's abstract) Statistics for childhood cancer demonstrate greatly improved survival rates over the last twenty years in the United States. Depending on the type of cancer, 58-88% of children and adolescents will be long-term, disease free survivors. While such statistics are encouraging, the nature and course of many cancers has changed from an inevitably fatal illness to a chronic illness that continues to carry the potential to threaten life. The American Cancer Society had identified adolescent cancer care, including psychosocial care, as a research priority. Yet, surprisingly few data-based studies have been reported on psychosocial adjustment of adolescents with cancer (AWC). In addition, systematically planned psychosocial intervention studies with AWC are rare, even though such interventions, tested over the last 2 decades in adults with cancer, show promising results. With over 200,000 childhood cancer survivors and the numbers projected to be 1 in 250 by the year 2000, it is imperative that adjustment issues for adolescents with cancer be addressed. The purposes of this study are to: 1) examine, longitudinally, the nature and patterns of change in resilience and quality of life through analysis of the Adolescent Resilience Model (ARM) in adolescents with cancer; and, 2) evaluate the extent to which patterns of resilience and quality of life change as a result of a family and adolescent network (FAN) intervention aimed at enhancing resilience and quality of life through individual, family and social protective factors in the ARM. The study design contains two components. To answer questions about relationships and causality among individual, family and social protective factors, illness-related and individual risk factors, and resilience and quality of life among adolescents with cancer, 11-19 year of age, a prospective longitudinal descriptive design will be used. The adolescents will be followed from diagnosis through the first of living with cancer. In the last 2 1/2 years of the project, after refinement and pilot work is done on the FAN intervention, a longitudinal experimental design w ill be implemented to evaluate changes that occur in the factors in the ARM as a result of a Family and Adolescent Network (FAN) intervention that is targeted to enhance individual, family, and social protective factors in the model and minimize illness- related and individual risk factors. The proposed total sample size is 243. Analysis of study aims will be accomplished through: 1) growth curve analysis to evaluate initial state, rate of change and stability; 2) common factor modeling of growth curve parameters; and 3) structural modeling of change factors over time and as a result of the intervention.