VIDEO RATE CALCIUM IMAGING FACILITY

美国国立卫生研究院资助的8名研究人员申请了资金，以建立一个强大而灵活的成像系统，该系统配备了膜片钳功能和快速溶液更换系统。主要的需要是测量细胞内钙离子浓度使用荧光指示器在视频速率，虽然其他离子也将被测量。所有的项目都直接来源于研究者目前资助的项目。健康科学中心没有这样的系统。大约一半的调查人员熟悉来自其他机构的这类设备。其他国家敏锐地意识到将这种分析应用于其调查所产生的好处。医学院院长和三位系主任高度致力于建立这一设施。该设施不仅将允许富有成效的研究小组继续做出有见地的贡献，而且还将成为丹佛地区具有类似想法的细胞信号研究人员的焦点。

Funds are requested by eight NIH-funded investigators to establish a powerful and flexible imaging system equipped with patch clamp capability and a rapid solution change system. The primary need is to measure intracellular Calcium ion concentration using fluorescent indicators at video rates, although other ions will also be measured. All of the projects arise directly from the investigators' currently funded projects. There is no such system at the Health Sciences Center. Approximately half of the investigators are familiar with such equipment from other institutions. The others have been acutely aware of the benefits arising from the application of such analysis to their investigations. The Dean of the School of Medicine and three department Chairpersons are highly committed to establishing this facility. The facility will serve not only to allow continued insightful contributions from a productive group of investigators, but it will serve as a focus for similarly minded investigators of cellular signaling in the Denver area.