课题基金 / 基金详情

RELATIONSHIP OF AGE TO CIRCADIAN DESYNCHRONY IN PERMANENT NIGHT SHIFT WORK

RELATIONSHIP OF AGE TO CIRCADIAN DESYNCHRONY IN PERMANENT NIGHT SHIFT WORK
长期夜班工作中年龄与昼夜节律不同步的关系
批准号：
6116938
负责人：
ROBERT L SACK
金额：
$3.13万
依托单位：
OREGON HEALTH & SCIENCE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6116938
关键词：
aging behavioral /social science research tag circadian rhythms clinical research environmental adaptation hormone therapy human subject human therapy evaluation melatonin occupations psychophysiology sleep

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中文摘要
翻译
总的目标是了解减少的生理基础 对长期夜班工作的耐受性通常与 老化，并试图改善适应永久夜间工作， 褪黑激素给药。 褪黑激素给药的适当时间 将作为一种方法进行测试，以提高对夜班工作的适应能力， 校正睡眠和潜在睡眠之间的任何相位角干扰 昼夜节律
英文摘要
The overall goal is to understand the physiological basis for the reduced tolerance to permanent night shift work that is commonly associated with aging, and to attempt to improve adaptation to permanent night work with melatonin administration. Appropriately-timed melatonin administration will be tested as a method to improve adaptation to night shift work by correcting any phase angle disturbance between sleep and underlying circadian rhythms.
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