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PRESENCE OF ENZYME PC4 IN TESTICULAR TUMOR

PRESENCE OF ENZYME PC4 IN TESTICULAR TUMOR
睾丸肿瘤中酶 PC4 的存在
批准号：
6219969
负责人：
THEODORE FRIEDMAN
金额：
$0.1万
依托单位：
LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6219969
关键词：
clinical research enzymes hormone related neoplasm /cancer human subject neoplastic transformation testis testis neoplasms

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中文摘要
翻译
激素以较大的非活性形式合成，然后通过酶消化激活。最近发现的一种酶PC4只存在于睾丸中。它在睾丸中的作用是未知的，它所作用的激素也是未知的。本研究旨在检测PC4在人类睾丸肿瘤中的存在，并观察它是否在肿瘤形成中起作用。在接下来的一年里，GCRC将收集更多的睾丸肿瘤。
英文摘要
Hormones are synthesized in larger inactive forms and then are activated by enzymatic digestion. A recently described enzyme, PC4, has been found only in the testis. Its role in the testis is unknown, as is the hormone that it acts upon. The present study is designed to test for the presence of PC4 in human testicular tumors and to see if it has a role in tumor formation. During the coming year additional testicular tumors will be collected by the GCRC.
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会议论文
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CLINICAL TRIAL: HORMONE GEL APPLIED TO WOMEN WITH PITUITARY GLAND PROBLEMS
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