DC HIV RELATED MALIGNANCY TISSUE/BIOLOGICAL FLUIDS BANK

这项提议的目标是开发一个全面的、用户友好的、 个人组织和生物体液样本库 显示出与艾滋病毒相关的恶性肿瘤。来自这家银行的材料将是 适用于对发病机制感兴趣的研究人员，以及 寻求改进艾滋病毒相关的诊断测试和治疗 恶性肿瘤。位于美国艾滋病毒/艾滋病中心的标本库 流行病使来自妇女、儿童和有色人种的材料 有很好的代表性。这样的组织库将满足广泛的 艾滋病毒相关恶性肿瘤领域的各种调查人员。至 实现这一目标，我们将建立华盛顿特区艾滋病毒相关恶性肿瘤 来自医院集团的组织/生物体液库联合体 为所有感染艾滋病毒的个人提供大部分护理 大都会地区的个人。 华盛顿特区艾滋病毒相关恶性肿瘤组织/生物体液库联合体 将收集、保存和维护一个全面的质量银行 患者所有肿瘤突起的组织和液体标本 艾滋病。将建立质量保证体系，以监测 收集和保存过程，并确保质量 分发给个别调查人员的材料。行政管理人员 将实施结构以保护患者的机密性，同时 为调查人员提供有关该病毒来源的准确信息 标本。 将保存每个患者的准确摘要病历 参与哥伦比亚特区艾滋病毒相关组织/生物体液库 允许临床与生物学发现相关联。

The goal of this proposal is to develop a comprehensive, user-friendly, bank of tissue and biological fluid specimens from individuals demonstrating HIV-related malignancies. Material from this bank will be available for researchers interested in pathogenesis, as well as those seeking to improve the diagnostic tests and therapies for HIV-related malignancies. A specimen bank in an epicenter of the U.S. HIV/AIDS epidemic allows material from women, children and people of color to be well represented. Such a tissue bank will meet the needs of a wide variety of investigators in the field of HIV-related malignancies. To achieve this goal we will establish the D.C. HIV-Related Malignancy Tissue/Biological Fluid Bank Consortium from the group of hospitals providing the majority of care to individuals of all HIV-infected individuals in the metropolitan D.C. area. The D.C. HIV-Related Malignancy Tissue/Biological Fluid Bank Consortium will collect, preserve, and maintain a comprehensive bank of quality tissue and fluid specimens of all neoplastic processes from patients with HIV disease. A quality assurance system will be established to monitor the collection and preservation processes and ensure the quality of material distributed to individual investigators. An administrative structure will be implemented to maintain patients confidentiality while providing investigators accurate information regarding the source of the specimens. Accurate abstracted medical records will be maintained on each patient participating in the D.C. HIV-Related Tissue/Biological Fluid Bank to allow clinical correlation to biologic findings.