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HIPPOCAMPAL COMPLEX VOLUME AND MEMORY DYSFUNCTION IN CUSHINGS SYNDROME

HIPPOCAMPAL COMPLEX VOLUME AND MEMORY DYSFUNCTION IN CUSHINGS SYNDROME
库欣综合征中的海马复合体体积和记忆功能障碍
批准号：
6244533
负责人：
MONICA N STARKMAN
金额：
$2.22万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-02-20 至 1997-11-30
来源：
https://reporter.nih.gov/project-details/6244533
关键词：
Cushing's syndrome clinical research drug adverse effect glucocorticoids hippocampus hormone therapy human subject human therapy evaluation hypercortisolism magnetic resonance imaging memory disorders neuropsychological tests

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中文摘要
翻译
这些研究将检验以下假设： 皮质醇过多导致记忆障碍，由毒素介导 糖皮质激素对海马体的影响。库欣综合征患者 疾病是检验假设的实验模型，使用 患者的神经心理测试和磁共振成像 治疗前和治疗后一年的海马体。
英文摘要
These studies will examine the hypothesis that sustained hypercortisolism results in memory disturbances mediated by the toxic effects of glucocorticoids on the hippocampus. Patients with Cushing's disease are the experiment model to test hypothesis, using neuropsychologic testing and magnetic resonance imaging of the hippocampus prior to and a year following treatment.
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会议论文
STEROIDS, COGNITION AND IMAGING IN CUSHING'S SYNDROME
VERB MEMORY & EMOTION PERCEPTION IN FMRI FOR CUSHING'S DISEASE PATIENTS
STEROIDS, COGNITION AND IMAGING IN CUSHING'S SYNDROME
VERB MEMORY & EMOTION PERCEPTION IN FMRI FOR CUSHING'S DISEASE PATIENTS
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