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EFFECT OF GROWTH HORMONE ON RENAL OSTEODYSTROPHY AND GLUCOSE METABOLISM

EFFECT OF GROWTH HORMONE ON RENAL OSTEODYSTROPHY AND GLUCOSE METABOLISM
生长激素对肾性骨营养不良和葡萄糖代谢的影响
批准号：
6246150
负责人：
ROBERT H MAK
金额：
$3.61万
依托单位：
STANFORD UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-05-15 至 1997-11-30
来源：
https://reporter.nih.gov/project-details/6246150
关键词：
bone density bone metabolism child (0-11) child physical development clinical research glucose clamp technique glucose metabolism hormone metabolism hormone therapy human subject human therapy evaluation insulin insulinlike growth factor minerals photon absorptiometry postnatal growth disorder renal rickets somatotropin

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中文摘要
翻译
生长激素对胰岛素、胰岛素样生长因子和胰岛素抵抗的影响 骨矿物质代谢将在生长障碍儿童中进行研究 死于肾衰竭 将通过双能X射线监测骨密度 吸收测定法和胰岛素代谢将通过高血糖 钳位方法学 主要研究终点为生长速度 标准差评分、胰岛素分泌和骨密度。
英文摘要
The effect of growth hormone on insulin, insulin-like growth factor and bone mineral metabolism will be studied in children with growth failure from renal failure. Bone density will be monitored by dual energy x-ray absorptiometry and insulin metabolism will be studied by hyperglycemic clamp methodology. Primary study end points will be growth velocity standard deviation score, insulin secretion and bone density.
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International Symposium on Growth and Nutrition in Chronic Kidney Disease
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