Discovery and characterisation of long noncoding RNAs in human neurological disorders

我们DNA中的许多区域会影响我们患上各种疾病的可能性，包括自闭症和精神分裂症等大脑疾病。然而，在这些区域中的许多区域没有发现基因，它们看起来是“空的”，这使得很难发现引发疾病的原因。该项目将使用一种强大的新技术来发现隐藏在这些所谓的“空”区域中的新基因，这些基因在大脑疾病中很重要，并研究它们如何导致疾病。

Numerous regions in our DNA influence how likely we are to develop various diseases, including brain disorders such as Autism and Schizophrenia. However, in many of these regions no genes have been found and they appear “empty”, making it difficult to uncover what’s triggering the disease. This project will use a powerful new technology to discover new genes hidden within these supposedly “empty” regions that are important in brain disorders and investigate how they contribute to disease.