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INTRATUMORAL/INTERSTITIAL THERAPY WITH HN-6600 IN REFRACOTRY GLIOBLASTOMA

INTRATUMORAL/INTERSTITIAL THERAPY WITH HN-6600 IN REFRACOTRY GLIOBLASTOMA
HN-6600 瘤内/间质治疗难治性胶质母细胞瘤
批准号：
6220079
负责人：
JEFFREY N BRUCE
金额：
$0.04万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6220079
关键词：
antineoplastics catheterization cerebrovascular surgery chemical conjugate clinical research drug administration routes drug screening /evaluation glioblastoma multiforme human subject human therapy evaluation interstitial neoplasm /cancer chemotherapy neoplasm /cancer relapse /recurrence

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中文摘要
翻译
一种新的实验性治疗复发的恶性脑肿瘤已经开发出来，它使用了一种名为靶向蛋白毒素的新型抗癌药物。本研究旨在探讨其能否安全有效地应用于恶性脑肿瘤患者。泵将通过外科手术放置在患者脑瘤中心的导管连续注入HN-66000 5至7天。
英文摘要
A new experimental treatment for recurrent malignant brain tumors has been developed that uses a new type of anticancer drug called a targeted protein toxin. This study is to find out if it can be used safely and effectively in patients with malignant brain tumors. A pump will continuously infuse HN-66000 for 5 to 7 days through a catheter that will be surgically placed into the center of the patient's brain tumor.
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Single Cell Analysis of the Infiltrative Margins of Glioblastoma and Post Treatment Recurrence
Single cell analysis of the infiltrative margins of glioblastoma and post-treatment recurrence
Single cell analysis of the infiltrative margins of glioblastoma and post-treatment recurrence
CHRONIC CONVECTION ENHANCED DELIVERY (CED) OF TOPOTECAN FOR GLIOBLASTOMA
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