OUTCOME OF PATIENTS W/CONGENITAL HEART MALFORMATIONS FOLLOWING FONTAN PROCEDURE

目的：评估患者的神经发育结局。 左心发育不良综合征(HLHS) 姑息。 方法：1)对HLHS患者进行神经发育测试；2) HLHS患者NDO与健康儿童NDO及儿童NDO的比较 患有非HLHS先天性心脏病损害的患者需要类似的 手术入路；3)评估这些患者中可能存在的因素 导致神经发育异常，包括结构性的 中枢神经系统异常和围手术期应激。 意义：可能会影响未来治疗慢性阻塞性肺疾病患者的方法 HLHS。

OBJECTIVE: Evaluate the neurodevelopmental outcome (NDO) of patients with hypoplastic left heart synbdrome (HLHS) following surgical palliation. APPROACH: 1) Perform neurodevelopmental testing on HLHS patients; 2) Compare NDO of HLHS patients to NDO of healthy children and to NDO of patients with non-HLHS congenital heart lesions requiring a similar surgical approach; 3) Evaluate factors in these patients which may contribute to abnormal neurodevelopment including structural abnormalities of the central nervous system and perioperative stresses. SIGNIFICANCE: May impact future approach to treating patients with HLHS.