EPR OF BOROHYDRIDE IRON PORPHYRIN COMPLEXES MODELS FOR REDUCTASES

除了催化氧化，许多基于卟啉的 酶系统减少底物，如在 细菌中发现的氢脱卤化蛋白。最新化学品 研究人员试图用铁卟啉模拟这一反应。 催化的硼氢化物还原。我们正试图确定 这些反应中的中间体，使用EPR来阐明 金属的氧化状态和a-阴离子自由基的性质 卟啉大循环。

In addition to catalytic oxidations, many porphyrin based enzymatic systems reduce substrates, such as in the hydrodehalogenation proteins found in bacteria. Recent chemical investigations have tried to model this reaction using iron porphyrin catalyzed borohydride reductions. We are attempting to determine the intermediates in these reactions, using EPR to elucidate both the oxidation state of the metal and the a anion radical nature of the porphyrinic macrocycle.