ALCOHOL RESEARCH--RISK AND PROTECTION IN ETHNIC GROUPS

加州大学圣地亚哥分校精神病学系 在此代表塔玛拉·L.独立科学家的墙 国家酒精滥用和酒精中毒研究所奖（KO 2） （NIAAA）。 建议设立的研究事业奖励计划的整体目标是 将候选人从临床和行政职责中解放出来， 可以投入几乎全部时间来继续和进一步发展她的研究 评估饮酒的风险和保护因素， 不同的民族。 亚裔美国人和美洲原住民 不同的模式，患病率和后果， 饮酒 据推测，这些差异是由于 生理和心理社会因素的结合。 这个应用程序有两个总体目标：1）完成两个项目 目前由NIAAA资助，专注于了解 遗传对亚裔美国人和原住民对酒精反应的影响 美国印第安人; 2）通过评估这些研究， 生物学和社会心理学的综合影响， 饮酒模式和问题在这些民族群体中使用 横截面的，最终是纵向的数据。 获得的结果 这些研究将提供重要的信息， 生物和环境方面的复杂关系 易受酒精中毒的伤害和保护。 这位候选人有 对酒精相关的研究做出了坚定的承诺。为她的活动 持续的职业发展将包括：1）密集的新培训 与领先的研究科学家在心理社会的重要性， 酒精使用和酒精问题的发展模型中的因素， 统计建模技术和纵向研究设计; 2） 高级结构建模和负责任行为课程 研究;和3）参加部门研讨会和科学 会议.

The University of California, San Diego (UCSD), Department of Psychiatry hereby applies on behalf of Tamara L. Wall for an Independent Scientist Award (KO2) from the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The overall aim of the proposed Research Career Award is to free the candidate from clinical and administrative duties so that she may devote nearly full-time to continue and develop further her research evaluating risk and protective factors for alcohol involvement within different ethnic groups. Asian Americans and Native American Indians vary greatly with respect to patterns, prevalences, and consequences of alcohol use. These differences are hypothesized to result from a combination of biological and psychosocial factors. This application has two overall goals: 1) to complete two projects currently funded by NIAAA focused on understanding the effects of genetic influences on response to alcohol in Asian Americans and Native American Indians; and 2) to expand upon these studies by evaluating the combined contributions of biological and psychosocial influences on alcohol drinking patterns and problems within these ethnic groups using cross-sectional, and eventually longitudinal, data. Results obtained from these studies will provide important information regarding the complex relationship between biological and environmental aspects of vulnerability to, and protection from, alcoholism. The candidate has made a strong commitment to alcohol-related research. Activities for her continued career development will include: 1) intensive new training with leading research scientists in the importance of psychosocial factors in developmental models of alcohol use and alcohol problems, statistical modeling techniques, and longitudinal research design; 2) coursework on advanced structural modeling and the responsible conduct of research; and 3) participation in department seminars and scientific meetings.