EFFECTS OF DENTAL TREATMENT DURING PREGNANCY ON CHILDHOOD DEVELOPMENT

工作总结：去年，我们分析了脐带汞的数据，发现母亲报告的一周吃鱼粉的数量与她的脐带汞水平之间存在统计上的显著关联。我们还发现，在怀孕期间拔除汞齐的数量与脐带汞水平之间存在统计上的显著关系。在分析这些数据的过程中，我们发现了数据中的一种模式，这表明它们是实验室分析中的一个问题。样本正在实验室重新分析，一旦重复测量，我们将重新进行分析。虽然其他研究人员已经使用脐带组织作为有机汞的生物监测媒介，但这是第一次尝试使用它来测量怀孕期间接触汞蒸气的情况。当数据可用时，我们将完成关于怀孕期间牙科治疗与脐带汞水平之间的关系的论文。今年，我们计划分析怀孕期间牙科治疗对儿童发育影响的更大队列。-脐带、汞、汞齐、牙科、鱼类消费、甲基汞、汞蒸气-人体受试者：仅采访、问卷或调查

Summary of Work: Last year, we analyzed the umbilical cord mercury data and found a statistically significant association between the number of fish meals a mother reported eating a week and her umbilical cord mercury level. We also found a statistically significant relationship between the number of amalgams removed during pregnancy and umbilical cord mercury levels. In the process of analyzing these data, we discovered a pattern in the data that suggested their had been a problem in the laboratory analysis. The samples are being reanalyzed in the laboratory and we will re-do our analysis once the measurements are repeated. Although other researchers have used cord tissue as a biologic monitoring medium for organic mercury, this is the first study to try to use it to measure exposure to mercury vapor during pregnancy. When the data are available we will finish the paper on the relationship between dental treatment during pregnancy and cord mercury levels. This year we plan to analyze the larger cohort for the effect of dental treatment during pregnancy on childhood development.. - umbilical cord, mercury, amalgams, dental, fish consumption, methyl mercury, mercury vapor - Human Subjects: Interview, Questionaires, or Surveys Only