A novel endogenous inhibitor for the treatment of diabetic nephropathy

在各种肾脏疾病中，包括最常见的终末期肾脏疾病，糖尿病肾病，需要确定导致肾衰竭的分子机制，以帮助确定新的靶点和开发更有效的治疗方法。这些研究强调了天然存在的内源性分子脂素作为肾损伤调节剂的潜力，这可能为我们提供一种解决糖尿病肾病问题的新方法。

In various kidney diseases including the most common cause of end stage kidney disease, diabetic nephropathy, identifying the molecular mechanisms responsible for kidney failure are needed to assist in defining new targets and to develop more effective treatments. The proposed studies highlight the potential of a naturally occurring endogenous molecule called Lipoxin, as a modulator of kidney injury which may provide us with a novel approach to tackle the problem of diabetic nephropathy.