EVALUATION OF A CONCEPTUAL MODEL OF ORGAN DONATION

这一修订提案是为了响应联邦政府提高全国器官捐献率的倡议而设计的。有充分的证据表明，对供体器官的需求远远超过了活体器官的捐赠率，而提高捐赠率是临床移植领域面临的最关键问题。到目前为止，研究工作主要集中在提高公众的态度和意愿，成为器官捐赠者，并通过无条件的科学努力来确定那些最能预测实际近亲捐赠同意的因素。由于器官捐献几乎完全取决于家庭成员的同意，因此我们必须加强对可能导致有利同意决定的变量的理解。使用Radecki和Jaccard开发的概念模型，我们将研究近亲的信仰和态度和知识的死者的捐赠意图器官捐赠决定的协会。根据现有文献，假设与捐赠决策相关的变量包括：近亲信仰结构，对器官捐赠的态度和应对资源。大约250名捐赠请求所针对的近亲将在请求提出后两周内接受电话采访，并在概念模型的指导下对几个变量进行评估。数据分析将使用分层逻辑回归。预计本研究的结果将提高我们对影响器官捐献同意的最突出的个人和背景因素的理解，并指导有效请求策略的制定。

This revised proposal is designed in response to the federal government's initiative to increase national organ donation rates. It is well documented that the need for donor organs far exceeds the rate at which viable organs are donated, and that increasing donation rates is the most critical issue facing the field of clinical transplantation. To date, research efforts have focused mostly on enhancing public attitudes and willingness to become organ donors with comparably less scientific effort to identify those factors that are most predictive of actual next-of-kin donation consent. Since organ donation depends almost exclusively on the consent of family members it is imperative that we enhance our understanding of those variables that are likely to lead to favorable consent decisions. Using a conceptual model developed by Radecki and Jaccard, we will examine the associations of next-of-kin beliefs and attitudes and knowledge of the deceased's donation intentions to organ donation decisions. Variables hypothesized to be associated with donation decisions based on the extant literature include: next-of-kin belief structure, attitude toward organ donation, and coping resources. Approximately 250 next-of-kin to whom a donation request was targeted will be interviewed by telephone within two weeks of the request and assessed on several variables guided by the conceptual model. Hierarchical logistic regression will be used in the data analysis. It is expected that results from this study will enhance our understanding of the most salient individual and contextual factors that affect organ donation consent and guide the development of effective request strategies.