TYPHOON 8600 VARIABLE MODE IMAGER

描述：(调查员？S摘要)：所需仪器为ABI 棱镜技术涉及多色荧光、化学荧光、 化学发光和放射性同位素检测在所有 研究学科。在此应用程序中，我们请求一个分子 动态台风8600可变模式成像器。这款最先进的成像器具有 能够执行所有多色荧光、化学荧光、 化学发光和无胶片放射自显影成像分析。这个 仪器仪表快速、易用，省钱，无需 胶片，占用最少的实验室空间，并可用于 广泛的应用，几乎涉及任何样品的成像。我们有 在大多数人中发现了对这种类型仪器的巨大需求 马歇尔大学医学院的活跃研究人员。在……里面 除了七人小组外，联邦政府资助的主要用户还拥有广泛的 研究兴趣，包括分子遗传学，毒理学，神经科学， 免疫学和细胞生物学，我们已经确定了一组较小的使用者和 潜在的外部用户，他们将从台风的访问中受益 8600成像器。虽然这种类型的仪器在许多研究中是标准的 设施方面，个人很难获得这样的仪器 像我们这样资金有限的小型机构的研究人员 资源。提供具有广泛功能的共享成像仪 台风8600将极大地增强我们迅速和成功地 完成我们资助的研究项目的许多具体目标。 这反过来又将促进我们研究所的研究人员的能力 在为一些与人类健康有关的问题贡献重要知识方面 这些问题是我们资助研究的长期目标。

DESCRIPTION: (Investigator?s Abstract): The instrument requested is the ABI prism Techniques involving multi-color fluorescence, chemifluorescence, chemiluminescence, and radioisotopic detection are abundantly used in all research disciplines. In this application, we are requesting a Molecular Dynamics Typhoon 8600 Variable Mode Imager. This state-of-the-art imager has the capability to perform all multi-color fluorescence, chemifluorescence, chemiluminescence, and filmless autoradiography imaging analyses. The instrumentation is quick, easy to use, saves money by eliminating the need for film, takes up a minimal amount of laboratory space, and can be used for a wide-variety of applications involving imaging of almost any sample. We have identified a tremendous need for this type of instrumentation among a majority of the active researchers at the Marshall University School of Medicine. In addition to a group of seven, federally funded major users with a wide-range of research interests, including molecular genetics, toxicology, neuroscience, immunology, and cell biology, we have identified a group of minor users and potential outside users who would greatly benefit from access to the Typhoon 8600 imager. While this type of instrumentation is standard at many research facilities, acquisition of such instrumentation is difficult by individual researchers at a small institution such as ours with limited financial resources. Availability of a shared imager with the wide capabilities of the Typhoon 8600 would greatly enhance our ability to quickly and successfully accomplish many of the specific objectives of our funded research projects. This, in turn, will facilitate the ability of researchers from our institution in contributing important knowledge toward a number of human health-related issues that are long-term goals of our grant-funded research.