EXTRAMURAL RESEARCH FACILITIES CONSTRUCTION: HIV VACCINE, AIDS & MALIGNANCIES

关于艾滋病描述（由申请人提供）：本申请要求资金用于动物服务大楼（ASB）增建二期，该大楼将在11,970平方米的面积内为544只非人类灵长类动物（NHPs）提供住房。最先进的设施。扩建将使俄勒冈地区灵长类动物研究中心（ORPRC）能够满足快速增长的研究需求，并符合美国农业部（USDA）关于扩大社会住房的新规定标准。俄勒冈健康与科学大学（OHSU）做出了重大承诺，提供了大约400万美元的资金来建造一个35,600平方英尺的建筑。添加到ASB的壳。一期工程占地面积13000平方米。该设施将容纳多达192名nhp，并提供行为检测室、办公室和新的笼子清洗区。各种研究领域的快速增长需要额外的NHP住房。目前NHP的住房是满的，导致以下问题：1)有限的能力，以满足现有的研究计划的需要或开始新的项目；2)延迟采购所需动物；3)由于缺乏弹性空间而延迟装修；4)延迟实施社会住房。本申请的具体目的是建造ASB添加物的第二期填充物，包括动物生物安全等级2 （ABL2）的安全壳，在17个动物饲养室、一个饲料储存室和一个程序室中容纳多达544名nhp。每个动物饲养室将在成对的笼子中包含32个nhp，以及大型群体游戏围栏，让动物群体定期体验增强的社会环境。

Regarding AIDS DESCRIPTION (provided by applicant): This application requests funds to construct Phase II infill to the Animal Services Building (ASB) addition that will provide housing for 544 non-human primates (NHPs) in an 11,970 sq. ft. state-of-the art facility. The expansion will enable the Oregon Regional Primate Research Center (ORPRC) to meet rapidly growing research needs, as well as comply with new United States Department of Agriculture (USDA) mandated standards for expanded social housing. The Oregon Health and Science University (OHSU) made a major commitment by providing approximately $4 million in funds to construct a 35,600 sq. ft. shell addition to the ASB. Phase I infill consists of a 13,000 sq. ft. facility that will house up to 192 NHPs, as well as provide behavioral testing rooms, and office and new cage wash areas. Rapid growth in various research areas necessitates additional NHP housing. Current NHP housing is full, resulting in the following problems: 1) limited ability to meet the needs of existing research programs or begin new projects; 2) delayed procurement of needed animals; 3) delayed renovations due to lack of flex space; and 4) delayed implementation of social housing. The Specific Aims of this application are to construct Phase II infill of the ASB addition, consisting of Animal Biosafety Level 2 (ABL2) containment housing for up to 544 NHPs in 17 animal holding rooms, a feed storage room and a procedure room. Each animal holding room will contain 32 NHPs in paired cages, as well as large group play enclosures to permit groups of animals to regularly experience an enhanced social environment.