CINGULATE CORTEX IN SELECTIVE ATTENTION--FMRI STUDY

拟议工作的目的是提供一个更好的理解 前扣带皮层（ACC）在选择性 关注 特别感兴趣的是阶段的确定 行政协调会参与调解冲突的程序 决议（Gehring，1993年）和援引决议所需的冲突程度 其活动。 拟议的实验将利用 Stroop任务，因为该任务提供了选择性的直接操纵。 关注 功能性MRI将用于检测任务特定变化 在ACC的活动中 第一个实验将确定ACC活性是否是 与反应干扰有关。 这将通过 确定其在Stroop任务中的活动是否依赖于 或者不一致的词命名合格的响应。第二 实验将确定ACC的活动是否依赖于 语义冲突的程度。 为此，增加行政协调会 在干扰条件下的活动将被检查一个函数 不一致词的相对语义值。 第三 实验将确定ACC的活动是否依赖于 反应阶段的冲突程度。 为此，增加行政协调会 在干扰条件下的活动将作为 刺激与反应映射的相对强度函数 与不一致的词相关。 更具体地了解行政协调会在以下方面的作用： 选择性关注对于医学领域是重要的，如最近 神经影像学研究将前扣带回功能障碍与注意力缺陷联系起来 在临床人群中观察到，例如患有 精神分裂症或注意力缺陷多动障碍。

The purpose of the proposed work is to provide a better understanding of the specific role(s) of anterior cingulate cortex (ACC) in selective attention. Of particular interest is the determination of the stages of processing at which the ACC is involved in mediation of conflict resolution (Gehring, 1993) and the degree of conflict required to invoke its activity. The proposed experiments will make use of variants of the Stroop task, as this task provides for direct manipulation of selective attention. Functional MRI will be used to detect task specific changes in the ACC's activity. The first experiment will establish whether or not ACC activity is linked to response interference. This will be accomplished by determining if its activity in the Stroop task is dependent on whether or not the incongruent word names an eligible response. The second experiment will determine if the ACC's activity is dependent on the degree of as semantic conflict present. To do so, increases in ACC activity during the interference condition will be examined a a function of the relative semantic value of the incongruent word. The third experiment will determine if the ACC's activity is dependent on the degree of conflict at the response stage. To do so, increases in ACC activity during the interference condition will be examined as a function of the relative strength of the stimulus to response mappings associated with the incongruent word. The development of a more specific understanding of the ACC's role in selective attention is of importance to the medical field, as recent neuroimaging studies have linked ACC dysfunction to attention deficits observed in clinical populations such as individual suffering from schizophrenia or attention-deficit-hyperactivity-disorder.