NETWORK RISKS AMONG INJECTING DRUG USERS

描述(由申请人提供)：在许多国家，新的注射吸毒者(IDU)面临感染艾滋病毒和 丙型肝炎(丙肝)。新的注射吸毒者感染风险增加，如果他们的风险 网络(即与他们吸毒或发生性关系的人)和社会 影响网络(即与之互动并对其产生影响的人 他们的行为)是高风险的。了解网络和行为风险如何 对于新注射器之间的感染来说，跨国家的感染是必不可少的 制定国际和地方公共卫生政策和预防 在注射吸毒者中抗击艾滋病和丙型肝炎流行的干预措施。比较 对不同国家新的注射吸毒者的研究有助于理解 社会和毒品使用环境的跨国差异以及 文化背景会影响新的注射吸毒者的网络和行为风险。 本提案是为获得R03国际探险基金而提交的 这项研究将涉及阿兰·尼格斯博士与 纽约的国家发展和研究机构和安妮博士 美国国家健康与医学研究所(INSERM)的洛维尔 379年，法国马赛。本研究的目的是考察网络 新吸毒者中感染艾滋病毒和丙型肝炎的行为风险(那些 在过去6年内开始注射毒品，年龄在18岁至30岁之间 年龄)。这项研究将对调查和艾滋病毒和丙型肝炎病毒进行初步分析 对纽约和马赛正在进行的注射吸毒者研究的测试数据进行比较 两市新增静脉吸毒人群的网络和行为风险。定性的 还将利用机构和人种学数据进行研究，以 探索药物使用和社会效益的差异程度 环境会影响新注射器的网络和行为风险。因为有 许多来自北非的注射吸毒者在马赛也将进行这项研究 探索性研究以了解跨国旅行模式 来自北非的注射吸毒者在法国南部和北非之间 与他们的网络和艾滋病毒和丙型肝炎病毒的行为风险有关。 调查和生物数据的初步分析结果和 从探索性的定性研究将被用来产生假设 并发展了未来更大规模的新的研究的概念和设计 这两个城市的注射器将作为RO1申请提交。

DESCRIPTION (provided by applicant): In many countries, new injecting drug users (IDUs) are at substantial risk of becoming infected with HIV and hepatitis C (HCV). New IDUs are at increased risk of infection if their risk networks (i.e., the people with whom they use drugs or have sex) and social influence networks (i.e., the people with whom they interact and who influence their behavior) are high risk. Understanding how network and behavioral risks for infection among new injectors vary cross-nationally is essential to the development of international and local public health policies and preventive interventions to combat the AIDS and HCV epidemic among IDUs. Comparative studies of new IDUs in different countries can contribute to an understanding of how cross-national differences in the social and drug using environment and cultural contexts can influence the network and behavioral risks of new IDUs. This proposal is submitted to obtain a R03 grant for exploratory international research that will involve a collaboration between Dr. Alan Neaigus of the National Development and Research Institutes, in New York City, and Dr. Anne Lovell of the National Institute of Health and Medical Research (INSERM), U 379, in Marseilles, France. The purpose of the research is to examine network and behavioral risks for HIV and HCV infection among new IDUs (those who started to inject drugs within the last 6 years and who are from 18 to 30 years of age). The study will conduct preliminary analyses of survey and HIV and HCV test data from ongoing studies of IDUs in New York and Marseilles to compare the network and behavioral risks of new IDUs in the two cities. Qualitative research using institutional and ethnographic data will also be conducted to explore the extent to which differences in the drug use and social benefit environments affect new injectors' network and behavioral risk. Since there are many IDUs of North African origin in Marseilles, the study will also conduct exploratory research to understand whether transnational travel patterns between Southern France and North Africa by IDUs of North African origin are related to their network and behavioral risks for HIV and HCV. Findings from the preliminary analyses of the survey and biological data and from the exploratory qualitative research will be used to generate hypotheses and to develop the conception and design of a future larger scale study of new injectors in the two cities that will be submitted as an RO1 application.