EARLY SOCIOECONOMIC & PSYCHOSOCIAL RISK FOR OBESITY

描述(改编自申请者的描述)：本K23的目标 建议提供与儿童肥胖症相关的研究培训。这个 申请人是一名学术儿科医生，曾在 自1983年以来，儿童一直处于贫困状态。她曾与非裔美国人、美国人 印第安人和西班牙裔美国人。肥胖症的流行比 在美国人数不足的少数族裔群体中非常严重，而且在一些 发展中国家。来自弱势家庭的儿童被置于 各种因素增加了肥胖的风险。这项提议依赖于 五个正在进行的纵向美国和国际样本丰富的增长， 关于受试者及其家人的人口统计和心理数据。这个 样本包括：来自密歇根州东南部的260名学龄前儿童； (各100人)来自最近呈现快速增长的美国印第安人人口 在出生体重和肥胖方面；150名哥斯达黎加儿童从1岁开始接受研究，谁 现在19岁；1000名智利人，他们现在5岁，从 4个月；3,400名芬兰男性和女性心血管疾病发病率高 疾病。本项目提出的研究、培训和研究计划如下 与涉及这5个纵向项目的活动密切相关。这些 正在进行的研究项目将成为继续收集数据的框架， 新的数据分析和比较研究。贝齐·罗佐夫博士，世界卫生组织 人类生长发育中心和儿科学教授是 项目导师。由少年儿童领袖组成的杰出委员会 营养、行为、发育、肥胖、生物统计学和健康 差异将指导培训并为研究提供建议。加根博士 建议探索行为和心理因素导致 幼儿肥胖的额外风险。而不是忽视了 在遗传学、营养学和体力活动方面，这项工作将促进 了解贫困在儿童肥胖中的作用。假设 儿童因以下原因而面临肥胖及其带来的健康问题 生物和社会因素，包括贫困、父母心理健康和 关于儿童营养和活动的父母决策将是 在五个不同的高危人群中进行了深入调查。如果肥胖症 预防，关键是要在多个层面上了解前兆和 针对那些可以修改以进行干预的因素。

DESCRIPTION (Adapted from applicant's description): The goal of this K23 proposal is to provide research training related to childhood obesity. The applicant is an academic pediatrician who has worked in settings serving children in poverty since 1983. She has worked with African American, American Indian and Hispanic American populations. The epidemic of obesity is more severe in underrepresented minority groups in the US and increasingly in some developing countries. Children from disadvantaged backgrounds are put at increased risk for obesity by a variety of factors. This proposal relies on five ongoing longitudinal US and international samples with rich growth, demographic and psychological data on the subjects and their families. The samples include: 260 preschool children from southeast Michigan; two cohorts (100 each) from an American Indian population showing recent rapid increases in birthweight and obesity; 150 Costa Rican children studied from 1 year, who are now age 19; 1000 Chileans who are currently 5 years old and studied since 4 months; and 3,400 Finnish men and women with high rates of cardiovascular disease. The research training and research plans proposed in this project are closely linked to activities involving these 5 longitudinal projects. These ongoing research projects will be the framework for continued data collection, new data analysis, and comparative study. Dr. Betsy Lozoff, Director of the Center for Human Growth and Development and Professor of Pediatrics is the project mentor. An outstanding committee composed of leaders in child nutrition, behavior, development, obesity, biostatistics and health disparities will direct the training and advise the research. Dr. Gahagan proposes to explore the behavioral and psychological factors that cause additive risk for obesity in young children. While not ignoring the importance of genetics, nutrition, and physical activity, this work will promote understanding the role of poverty in childhood obesity. The hypothesis that children are put at risk for obesity and its consequent health problems by biologic and social factors including poverty, parental mental health, and parental-decision making about childhood nutrition and activity will be examined in depth in five different populations at risk. If obesity is to be prevented, it is critical to understand the precursors on multiple levels and target those factors that are modifiable for intervention.