TRAINING PROGRAM IN CANCER BIOLOGY

产品说明： 这是一项为医学博士提供培训支持的建议， 医学博士/哲学博士、 和博士 博士后研究员（共7人），从事研究 癌症生物学的兴趣集中在血液肿瘤学 以色列贝斯医学系-女执事医疗部 中心 我们提供一个多学科的计划，包括教学 教学，正在进行的期刊俱乐部和研讨会，以及实验室研究。 课程的重要内容包括教师的密切监督 顾问和培训补助金指导委员会，课程工作，并经常 学员和实习教师之间的互动。 拟议方案是 在本杰明·G博士的指导下 Neel和Associate Program 主任史蒂文·巴尔克博士和迈克尔·阿特金斯。实习教师基于 主要 在贝丝以色列女执事医疗中心，在 医学和病理学系。 此外，一些被选中的教师 从周围的哈佛医学区机构（例如，Dana-Farber癌症 布里格姆妇女医院，HMS）已被选中， 参与基于他们的研究的相关性和实力， 培训记录，以及他们与其他成员的频繁互动， 培训教师。 参与的教师有很强的研究记录 成就，资金充足的研究计划，以及广泛和成功的 培训记录 在五个研究重点领域， 包括：信号转导和细胞周期控制;血管生成; 白血病发生;上皮细胞生物学和癌发生;和免疫生物学 和免疫疗法。 指导该计划的首要原则是， 将基础研究成果迅速转化到临床上， 临床医生接受现代生物科学的广泛而深入的培训 和研究，而博士。 水平的研究人员补充他们的培训， 对癌症病理学的深入了解。 我们的计划，设计与这些 目标，包括癌症生物学的教学课程，沿着 经常参加研讨会和期刊俱乐部，以加强课程学习。 虽然这是一个新的应用程序，培训学院和贝丝以色列- 女执事 医学中心血液肿瘤科有一个长期的， 培养成功院士的成功记录。 我们的培训计划 是高度选择性的，根据这项建议支持的候选人将 代表了一个高度选择和选择的年轻研究者群体， 对未来成就的承诺。

DESCRIPTION: This is a proposal to provide training support to M.D., M.D./Ph.D., and Ph.D. postdoctoral fellows (total of 7) with research interests in Cancer Biology to be centered within the Hematology-Oncology Division of the Department of Medicine of Beth Israel-Deaconess Medical Center. We offer a multi-disciplinary program consisting of didactic instruction, ongoing journal clubs and seminars, and laboratory research. Important elements of the curriculum include close supervision by faculty advisors and the Training Grant Steering Committee, course work, and frequent interactions amongst trainees and trainee faculty. The proposed program is under the direction of Dr. Benjamin G. Neel, and the Associate Program Directors, Dr. Steven Balk and Michael Atkins. Trainee faculty are based predominantly at the Beth Israel-Deaconess Medical Center, within the Departments of Medicine and Pathology. In addition, a few selected faculty from surrounding Harvard Medical Area Institutions (e.g., Dana-Farber Cancer I n stitute, Brigham and Women's Hospital, HMS) have been selected to participate based both on the relevance and strength of their research and training records, and on their frequent interactions with other members of the training faculty. The participating faculty have strong records of research accomplishments, well-funded research programs, and extensive and successful training records. Particular strength is found in five research focus areas, which include: Signal Transduction and Cell Cycle Control; Angiogenesis; Leukemogenesis; Epithelial Cell Biology and Carcinogenesis; and Immunobiology and Immunotherapy. The overarching principle guiding this program is that for the rapid translation of basic research findings to the bedside, it is vital that clinicians receive broad and deep training in modern biological science and research, while Ph.D. level researchers supplement their training with insights into the pathobiology of cancer. Our program, designed with these goals in mind, includes didactic coursework in Cancer Biology along with frequent seminars and journal clubs to soldify learning in the courses. Although this is a new application, the training Faculty and the Beth Israel- Deaconess Medical Center Hematology-Oncology Division have a long and successful record of training successful academicians. Our training program is highly selective, and candidates for support under this proposal will represent a highly selected and select group of young investigators with great promise for future accomplishments.