STEERABLE MICROFABRICATED MICROELECTRODE DRIVE

描述：(改编自申请者摘要) 这项可行性研究的目标是开发一种新型的静电 用于实现微电极阵列的微致动器技术 在用于记录细胞外电位的可控配置中 成群的神经元。需要开发一种微电极定位 推动电极在大脑中的精确放置和转向。这是意料之中的 这使得研究人员能够独立地长期控制和重新定位 植入动物体内的微电极阵列将显著进步 神经生理学研究。努力会发展出困难的 微执行器技术，满足位移、力、稳定性和 脑内微电极定位的精度要求及发展 一种集成的多通道微驱动系统及其关联 互连、信号和电力传输以及封装要求。这个 项目应克服在此之前阻碍的主要技术障碍 精确的细胞外定位和长期记录，只需最少的 行为受试者清醒时的障碍。

DESCRIPTION:(adapted from applicant's abstract) The goal of this feasibility study is to develop a novel electrostatic microactuator technology for the purpose of implementing microelectrode arrays in a steerable configuration for recording extracellular potentials from populations of neurons. There is a need to develop a microelectrode positioning drive for precise placement and steering of electrodes in brain. It is expected that enabling researchers to independently steer and reposition chronically implanted microelectrode arrays in behaving animals will significantly advance neurophysiological research. The effort will develop the difficult microactuator technology that satisfies the displacement, force, stability, and precision requirements for microelectrode positioning in the brain and develop an integrated multi-channel microdrive system with its associated interconnects, signal and power delivery, and packaging requirements. The project should overcome a major technological barrier that heretofore blocked precision extracellular positioning and long-term recording with minimal hindrance from awake behaving subjects.